Homo sapiens Gene: ZNF197
Summary
InnateDB Gene IDBG-28876.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol ZNF197
Gene Name zinc finger protein 197
Synonyms D3S1363E; P18; VHLaK; ZKSCAN9; ZNF166; ZNF20; ZSCAN41
Species Homo sapiens
Ensembl Gene ENSG00000186448
Encoded Proteins
zinc finger protein 197
zinc finger protein 197
zinc finger protein 197
zinc finger protein 197
zinc finger protein 197
zinc finger protein 197
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene product belongs to the zinc finger protein superfamily, members of which are regulatory proteins characterized by nucleic acid-binding zinc finger domains. The encoded protein contains 20 tandemly arrayed C2H2-type zinc fingers, a Kruppel-associated box (KRAB) domain, and a SCAN box. This transcript turns over rapidly and contains 3' UTR AUUUA motifs, which are often a hallmark of rapid turnover. It is overexpressed in some thyroid papillary carcinomas. This gene is located in a cluster of zinc finger genes at 3p21. Two alternatively spliced transcripts encoding different isoforms have been described. [provided by RefSeq, Jul 2008]
This gene product belongs to the zinc finger protein superfamily, members of which are regulatory proteins characterized by nucleic acid-binding zinc finger domains. The encoded protein contains 20 tandemly arrayed C2H2-type zinc fingers, a Kruppel-associated box (KRAB) domain, and a SCAN box. This transcript turns over rapidly and contains 3\' UTR AUUUA motifs, which are often a hallmark of rapid turnover. It is overexpressed in some thyroid papillary carcinomas. This gene is located in a cluster of zinc finger genes at 3p21. Two alternatively spliced transcripts encoding different isoforms have been described. [provided by RefSeq, Jul 2008]
Gene Information
Type Protein coding
Genomic Location Chromosome 3:44584888-44648471
Strand Forward strand
Band p21.31
Transcripts
ENST00000383745 ENSP00000373251
ENST00000383744 ENSP00000373250
ENST00000344387 ENSP00000345809
ENST00000334075 ENSP00000334616
ENST00000396058 ENSP00000379370
ENST00000412641 ENSP00000394713
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 12 experimentally validated interaction(s) in this database.
Experimentally validated
Total 12 [view]
Protein-Protein 12 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Gene Ontology

Molecular Function
Accession GO Term
GO:0003676 nucleic acid binding
GO:0003677 DNA binding
GO:0003700 sequence-specific DNA binding transcription factor activity
GO:0046872 metal ion binding
Biological Process
GO:0006351 transcription, DNA-templated
GO:0006355 regulation of transcription, DNA-templated
Cellular Component
GO:0005622 intracellular
GO:0005634 nucleus
Orthologs
No orthologs found for this gene
Pathways
NETPATH
REACTOME
Generic Transcription Pathway pathway
Gene Expression pathway
KEGG
INOH
PID NCI
Cross-References
SwissProt
TrEMBL
UniProt Splice Variant
Entrez Gene
UniGene Hs.157035
RefSeq NM_001024855 NM_006991 XM_005264783
HUGO
OMIM
CCDS CCDS2717 CCDS33743
HPRD 10322
IMGT
EMBL
GenPept
RNA Seq Atlas