Version 5.4
Homo sapiens Gene: SLC6A20
Summary
InnateDB Gene IDBG-29682.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol SLC6A20
Gene Name solute carrier family 6 (proline IMINO transporter), member 20
Synonyms
Species Homo sapiens
Ensembl Gene ENSG00000163817
Encoded Proteins
IDBP-29684
solute carrier family 6 (proline IMINO transporter), member 20
IDBP-29686
solute carrier family 6 (proline IMINO transporter), member 20
IDBP-374349
solute carrier family 6 (proline IMINO transporter), member 20
IDBP-380391
solute carrier family 6 (proline IMINO transporter), member 20
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary Transport of small hydrophilic substances across cell membranes is mediated by substrate-specific transporter proteins which have been classified into several families of related genes. The protein encoded by this gene is a member of the subgroup of transporter with unidentified substrates within the Na+ and Cl- coupled transporter family. This gene is expressed in kidney, and its alternative splicing generates 2 transcript variants. [provided by RefSeq, Jul 2008]
Gene Information
Type Protein coding
Genomic Location Chromosome 3:45755450-45796535
Strand Reverse strand
Band p21.31
Transcripts
ENST00000353278 ENSP00000296133
ENST00000358525 ENSP00000346298
ENST00000413781 ENSP00000395506
ENST00000456124 ENSP00000404310
ENST00000473146
ENST00000493980
ENST00000470226
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
Gene Ontology

Molecular Function
Accession GO Term
GO:0005328 neurotransmitter:sodium symporter activity
GO:0015171 amino acid transmembrane transporter activity
Biological Process
GO:0006811 ion transport
GO:0006836 neurotransmitter transport
GO:0006865 amino acid transport
GO:0015816 glycine transport
GO:0015824 proline transport
GO:0055085 transmembrane transport
Cellular Component
GO:0005886 plasma membrane
GO:0005887 integral component of plasma membrane
GO:0016021 integral component of membrane
GO:0016324 apical plasma membrane
Orthologs
Species
Mus musculus
Bos taurus
Gene ID
Gene Order
ENSMUSG00000036814
View Gene Order
ENSBTAG00000031340
Not yet available
Pathways
NETPATH
REACTOME
REACT_20506
Na+/Cl- dependent neurotransmitter transporters pathway
REACT_19305
Transport of glucose and other sugars, bile salts and organic acids, metal ions and amine compounds pathway
REACT_13796
Amino acid transport across the plasma membrane pathway
REACT_19397
Transport of inorganic cations/anions and amino acids/oligopeptides pathway
REACT_15518
Transmembrane transport of small molecules pathway
REACT_19118
SLC-mediated transmembrane transport pathway
KEGG
INOH
PID NCI
Cross-References
SwissProt
TrEMBL
UniProt Splice Variant
Entrez Gene
UniGene Hs.413095
RefSeq NM_020208 NM_022405 XM_005265236
HUGO
OMIM
CCDS CCDS2730 CCDS43077
HPRD 16128
IMGT
EMBL
GenPept
RNA Seq Atlas

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca