Version 5.4
Homo sapiens Gene: MORC3
Summary
InnateDB Gene IDBG-2971.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol MORC3
Gene Name MORC family CW-type zinc finger 3
Synonyms NXP2; ZCW5; ZCWCC3
Species Homo sapiens
Ensembl Gene ENSG00000159256
Encoded Proteins
IDBP-228122
MORC family CW-type zinc finger 3
IDBP-601202
MORC family CW-type zinc finger 3
IDBP-585894
MORC family CW-type zinc finger 3
IDBP-600121
MORC family CW-type zinc finger 3
IDBP-589621
MORC family CW-type zinc finger 3
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene encodes a protein that localizes to the nuclear matrix. The protein also has RNA binding activity, and has a predicted coiled-coil domain. [provided by RefSeq, Jul 2008]
Gene Information
Type Protein coding
Genomic Location Chromosome 21:36320189-36386148
Strand Forward strand
Band q22.12
Transcripts
ENST00000400485 ENSP00000383333
ENST00000492336
ENST00000487909
ENST00000485933
ENST00000485299
ENST00000484028
ENST00000546482 ENSP00000449467
ENST00000549948 ENSP00000447562
ENST00000551788 ENSP00000448357
ENST00000551367
ENST00000552581 ENSP00000449966
ENST00000547657
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 6 experimentally validated interaction(s) in this database.
They are also associated with 3 interaction(s) predicted by orthology.
Experimentally validated
Total 6 [view]
Protein-Protein 6 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 3 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0005524 ATP binding
GO:0008270 zinc ion binding
Biological Process
GO:0006468 protein phosphorylation
GO:0007569 cell aging
GO:0009791 post-embryonic development
GO:0018105 peptidyl-serine phosphorylation
GO:0048147 negative regulation of fibroblast proliferation
GO:0050821 protein stabilization
GO:0051457 maintenance of protein location in nucleus
Cellular Component
GO:0005634 nucleus
GO:0005654 nucleoplasm
GO:0016605 PML body
Orthologs
Species
Mus musculus
Bos taurus
Gene ID
Gene Order
ENSMUSG00000039456
View Gene Order
ENSBTAG00000011876
Not yet available
Cross-References
SwissProt
TrEMBL
UniProt Splice Variant
Entrez Gene
UniGene Hs.421150
RefSeq NM_015358 XM_006723985 XM_006723986
HUGO
OMIM
CCDS CCDS42924
HPRD 10316
IMGT
EMBL
GenPept
RNA Seq Atlas

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca