Version 5.4
Homo sapiens Gene: USP17L11
Summary
InnateDB Gene IDBG-298136.5
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol USP17L11
Gene Name ubiquitin specific peptidase 17-like family member 11
Synonyms
Species Homo sapiens
Ensembl Gene ENSG00000233136
Encoded Proteins
IDBP-362614
ubiquitin carboxyl-terminal hydrolase 17
IDBP-812049
ubiquitin specific peptidase 17-like family member 11
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
InnateDB Annotation
Summary
PMID 20368735
USP17 is required for virus-induced RIG-I- and melanoma differentiation-associated protein-5 (MDA5)-mediated type I IFN signaling and functions through deubiquitination of RIG-I and MDA5 to regulate virus-induced type I IFN signaling.
Entrez Gene
Summary Currently no Entrez Summary Available. You might want to check the Summary Sections of the Orthologs.
Gene Information
Type Protein coding
Genomic Location Chromosome 4:9215405-9217356
Strand Forward strand
Band p16.1
Transcripts
ENST00000457736 ENSP00000400880
ENST00000613973 ENSP00000477697
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
Gene Ontology

Molecular Function
Accession GO Term
GO:0008234 cysteine-type peptidase activity
GO:0036459 ubiquitinyl hydrolase activity
Biological Process
GO:0006511 ubiquitin-dependent protein catabolic process
GO:0045087 innate immune response (InnateDB)
Cellular Component
GO:0005634 nucleus
GO:0005783 endoplasmic reticulum
Orthologs
No orthologs found for this gene
Cross-References
SwissProt C9JVI0
TrEMBL
UniProt Splice Variant
Entrez Gene 101930650
UniGene Hs.553810 Hs.722783 Hs.723053
RefSeq NM_001256854
HUGO HGNC:44439
OMIM
CCDS CCDS59455
HPRD
IMGT
EMBL AC108519
GenPept
RNA Seq Atlas 100287178 101930650

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca