Version 5.4
Homo sapiens Gene: SEMA4B
Summary
InnateDB Gene IDBG-29866.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol SEMA4B
Gene Name sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4B
Synonyms SEMAC; SemC
Species Homo sapiens
Ensembl Gene ENSG00000185033
Encoded Proteins
IDBP-29870
sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4B
IDBP-380327
sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4B
IDBP-595547
sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4B
IDBP-584822
sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4B
IDBP-597897
sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4B
IDBP-602661
sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4B
IDBP-595852
sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4B
IDBP-585149
sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4B
IDBP-600109
sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4B
IDBP-596602
sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4B
IDBP-596913
sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4B
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary Currently no Entrez Summary Available. You might want to check the Summary Sections of the Orthologs.
Gene Information
Type Protein coding
Genomic Location Chromosome 15:90160604-90229679
Strand Forward strand
Band q26.1
Transcripts
ENST00000332496 ENSP00000332204
ENST00000411539 ENSP00000394720
ENST00000559322 ENSP00000453272
ENST00000559300 ENSP00000452957
ENST00000561085 ENSP00000453951
ENST00000558895 ENSP00000453705
ENST00000560263
ENST00000559792 ENSP00000453563
ENST00000560089 ENSP00000453484
ENST00000558051
ENST00000560003
ENST00000558848
ENST00000558065
ENST00000558975
ENST00000559074 ENSP00000453804
ENST00000560993
ENST00000561252
ENST00000559983 ENSP00000453866
ENST00000559247 ENSP00000454068
ENST00000561321
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 2 experimentally validated interaction(s) in this database.
They are also associated with 3 interaction(s) predicted by orthology.
Experimentally validated
Total 2 [view]
Protein-Protein 2 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 3 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0004872 receptor activity
GO:0005515 protein binding
Biological Process
GO:0007275 multicellular organismal development
GO:0007399 nervous system development
GO:0030154 cell differentiation
Cellular Component
GO:0005886 plasma membrane
GO:0016020 membrane
GO:0016021 integral component of membrane
GO:0045202 synapse
Orthologs
Species
Mus musculus
Bos taurus
Gene ID
Gene Order
ENSMUSG00000030539
View Gene Order
ENSBTAG00000021273
Not yet available
Pathways
NETPATH
NetPath_24
TSLP pathway
REACTOME
KEGG
hsa04360
Axon guidance pathway
INOH
PID NCI
Cross-References
SwissProt
TrEMBL H0YNC4
UniProt Splice Variant
Entrez Gene 10509
UniGene Hs.474935 Hs.736106
RefSeq NM_020210 NM_198925 XM_005254830
HUGO HGNC:10730
OMIM
CCDS CCDS45347
HPRD 10217
IMGT
EMBL AC091167
GenPept
RNA Seq Atlas 10509

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca