Homo sapiens Gene: ABCC11 | |||||||||||||
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Summary | |||||||||||||
InnateDB Gene | IDBG-29877.6 | ||||||||||||
Last Modified | 2014-10-13 [Report errors or provide feedback] | ||||||||||||
Gene Symbol | ABCC11 | ||||||||||||
Gene Name | ATP-binding cassette, sub-family C (CFTR/MRP), member 11 | ||||||||||||
Synonyms | |||||||||||||
Species | Homo sapiens | ||||||||||||
Ensembl Gene | ENSG00000121270 | ||||||||||||
Encoded Proteins |
ATP-binding cassette, sub-family C (CFTR/MRP), member 11
ATP-binding cassette, sub-family C (CFTR/MRP), member 11
ATP-binding cassette, sub-family C (CFTR/MRP), member 11
ATP-binding cassette, sub-family C (CFTR/MRP), member 11
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Protein Structure | |||||||||||||
Useful resources | Stemformatics EHFPI ImmGen | ||||||||||||
Entrez Gene | |||||||||||||
Summary |
The protein encoded by this gene is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). This ABC full transporter is a member of the MRP subfamily which is involved in multi-drug resistance. The product of this gene participates in physiological processes involving bile acids, conjugated steroids, and cyclic nucleotides. In addition, a SNP in this gene is responsible for determination of human earwax type. This gene and family member ABCC12 are determined to be derived by duplication and are both localized to chromosome 16q12.1. Multiple alternatively spliced transcript variants have been described for this gene. [provided by RefSeq, Jul 2008] |
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Gene Information | |||||||||||||
Type | Protein coding | ||||||||||||
Genomic Location | Chromosome 16:48166910-48247568 | ||||||||||||
Strand | Reverse strand | ||||||||||||
Band | q12.1 | ||||||||||||
Transcripts | |||||||||||||
Interactions | |||||||||||||
Number of Interactions |
This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
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Gene Ontology | |||||||||||||
Molecular Function |
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Biological Process |
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Cellular Component |
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Orthologs | |||||||||||||
No orthologs found for this gene | |||||||||||||
Pathways | |||||||||||||
NETPATH | |||||||||||||
REACTOME |
ABC-family proteins mediated transport pathway
Transmembrane transport of small molecules pathway
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KEGG |
ABC transporters pathway
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INOH | |||||||||||||
PID NCI | |||||||||||||
Cross-References | |||||||||||||
SwissProt | |||||||||||||
TrEMBL | |||||||||||||
UniProt Splice Variant | |||||||||||||
Entrez Gene | |||||||||||||
UniGene | Hs.652267 | ||||||||||||
RefSeq | NM_032583 NM_033151 NM_145186 | ||||||||||||
HUGO | |||||||||||||
OMIM | |||||||||||||
CCDS | CCDS10732 CCDS10733 | ||||||||||||
HPRD | 06127 | ||||||||||||
IMGT | |||||||||||||
EMBL | |||||||||||||
GenPept | |||||||||||||
RNA Seq Atlas | |||||||||||||