Version 5.4
Homo sapiens Gene: TRIM4
Summary
InnateDB Gene IDBG-30094.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol TRIM4
Gene Name tripartite motif containing 4
Synonyms
Species Homo sapiens
Ensembl Gene ENSG00000146833
Encoded Proteins
IDBP-30096
tripartite motif containing 4
IDBP-30098
tripartite motif containing 4
IDBP-30100
tripartite motif containing 4
IDBP-383073
tripartite motif containing 4
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary The protein encoded by this gene is a member of the tripartite motif (TRIM) family. The TRIM motif includes three zinc-binding domains, a RING, a B-box type 1 and a B-box type 2, and a coiled-coil region. The protein localizes to cytoplasmic bodies. Its function has not been identified. Alternatively spliced transcript variants that encode different isoforms have been described.[provided by RefSeq, Jul 2010]
Gene Information
Type Protein coding
Genomic Location Chromosome 7:99876958-99919600
Strand Reverse strand
Band q22.1
Transcripts
ENST00000355947 ENSP00000348216
ENST00000349062 ENSP00000275736
ENST00000354241 ENSP00000346186
ENST00000447480 ENSP00000396229
ENST00000496896
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 8 experimentally validated interaction(s) in this database.
Experimentally validated
Total 8 [view]
Protein-Protein 7 [view]
Protein-DNA 1 [view]
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Gene Ontology

Molecular Function
Accession GO Term
GO:0005515 protein binding
GO:0008270 zinc ion binding
GO:0046872 metal ion binding
Biological Process
GO:0070206 protein trimerization
Cellular Component
GO:0005622 intracellular
GO:0005737 cytoplasm
GO:0005886 plasma membrane
Orthologs
No orthologs found for this gene
Cross-References
SwissProt Q9C037
TrEMBL B4DEC5
UniProt Splice Variant
Entrez Gene 89122
UniGene Hs.50749
RefSeq NM_033017 NM_033091
HUGO HGNC:16275
OMIM
CCDS CCDS5679 CCDS5678
HPRD 15556
IMGT
EMBL AC011904 AF220023 AF220024 AK293565 BC011763 BC025949 CH236956 CH471091
GenPept AAG53477 AAG53478 AAH11763 AAH25949 AAS07396 AAS07397 AAS07398 BAG57036 EAL23864 EAL23865 EAW76625 EAW76626
RNA Seq Atlas 89122

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca