Version 5.4
Homo sapiens Gene: ZNF443
Summary
InnateDB Gene IDBG-30373.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol ZNF443
Gene Name zinc finger protein 443
Synonyms ZK1
Species Homo sapiens
Ensembl Gene ENSG00000180855
Encoded Proteins
IDBP-30375
zinc finger protein 443
IDBP-372791
zinc finger protein 443
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary Zinc finger proteins (ZNFs) bind DNA and, through this binding, regulate gene transcription. Most ZNFs contain conserved C2H2 motifs and are classified as Kruppel-type zinc fingers. For a general description of these proteins, see ZNF91 (MIM 603971).[supplied by OMIM, Jul 2002]
Gene Information
Type Protein coding
Genomic Location Chromosome 19:12429707-12441112
Strand Reverse strand
Band p13.2
Transcripts
ENST00000301547 ENSP00000301547
ENST00000436821 ENSP00000389105
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 5 experimentally validated interaction(s) in this database.
Experimentally validated
Total 5 [view]
Protein-Protein 2 [view]
Protein-DNA 3 [view]
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Gene Ontology

Molecular Function
Accession GO Term
GO:0003676 nucleic acid binding
GO:0003677 DNA binding
GO:0046872 metal ion binding
Biological Process
GO:0006351 transcription, DNA-templated
GO:0006355 regulation of transcription, DNA-templated
GO:0006915 apoptotic process
GO:0006950 response to stress
Cellular Component
GO:0005622 intracellular
GO:0005634 nucleus
Orthologs
No orthologs found for this gene
Pathways
NETPATH
REACTOME
REACT_12627
Generic Transcription Pathway pathway
REACT_71
Gene Expression pathway
KEGG
INOH
PID NCI
Cross-References
SwissProt
TrEMBL F8WDY2
UniProt Splice Variant
Entrez Gene 10224
UniGene Hs.720755
RefSeq NM_005815 XM_005259705
HUGO HGNC:20878
OMIM 606697
CCDS CCDS32918
HPRD 09460
IMGT
EMBL AC008758
GenPept
RNA Seq Atlas 10224

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca