Homo sapiens Gene: TCEB3C
Summary
InnateDB Gene IDBG-3070.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol TCEB3C
Gene Name transcription elongation factor B polypeptide 3C (elongin A3)
Synonyms
Species Homo sapiens
Ensembl Gene ENSG00000183791
Encoded Proteins
transcription elongation factor B polypeptide 3C (elongin A3)
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary The SIII (or elongin) transcription elongation factor complex stimulates the rate of transcription elongation by RNA polymerase II by suppressing the transient pausing of the polymerase at many sites along the DNA template. This complex is a heterotrimer, composed of the transcriptionally active subunit A, A2 or A3 (or elongin A, A2 or A3) and two regulatory subunits, B and C (or elongin B and C). This gene encodes subunit A3. A3 and A are ubiquitously expressed, whereas A2 is specifically expressed in the testis. [provided by RefSeq, Mar 2010]
Gene Information
Type Protein coding
Genomic Location Chromosome 18:47028202-47030078
Strand Reverse strand
Band q21.1
Transcripts
ENST00000330682 ENSP00000328232
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 3 experimentally validated interaction(s) in this database.
Experimentally validated
Total 3 [view]
Protein-Protein 3 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Gene Ontology

Molecular Function
Accession GO Term
GO:0003677 DNA binding
Biological Process
GO:0006351 transcription, DNA-templated
GO:0006355 regulation of transcription, DNA-templated
Cellular Component
GO:0005634 nucleus
GO:0016021 integral component of membrane
Orthologs
No orthologs found for this gene
Cross-References
SwissProt Q8NG57
TrEMBL
UniProt Splice Variant
Entrez Gene 162699
UniGene Hs.742303
RefSeq NM_145653 XM_005276637 XM_006722590 XM_006726764 XM_006726766
HUGO HGNC:24617
OMIM
CCDS CCDS11931
HPRD 15479
IMGT
EMBL AB076840 AC012254
GenPept BAC01113
RNA Seq Atlas 100506888 101060464 101929858 101930171 102725042 102725060 162699