Homo sapiens Gene: FBXW9
Summary
InnateDB Gene IDBG-30733.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol FBXW9
Gene Name F-box and WD repeat domain containing 9
Synonyms
Species Homo sapiens
Ensembl Gene ENSG00000132004
Encoded Proteins
F-box and WD repeat domain containing 9
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary Members of the F-box protein family, such as FBXW9, are characterized by an approximately 40-amino acid F-box motif. SCF complexes, formed by SKP1 (MIM 601434), cullin (see CUL1; MIM 603034), and F-box proteins, act as protein-ubiquitin ligases. F-box proteins interact with SKP1 through the F box, and they interact with ubiquitination targets through other protein interaction domains (Jin et al., 2004 [PubMed 15520277]).[supplied by OMIM, Mar 2008]
Gene Information
Type Protein coding
Genomic Location Chromosome 19:12688053-12696643
Strand Reverse strand
Band p13.13
Transcripts
ENST00000393261 ENSP00000376945
ENST00000587296 ENSP00000465854
ENST00000587955 ENSP00000465387
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 7 experimentally validated interaction(s) in this database.
Experimentally validated
Total 7 [view]
Protein-Protein 7 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Gene Ontology

Molecular Function
Accession GO Term
GO:0005515 protein binding
Biological Process
GO:0031146 SCF-dependent proteasomal ubiquitin-dependent protein catabolic process
Cellular Component
Orthologs
Species
Mus musculus
Bos taurus
Gene ID
Gene Order
Not yet available
Pathways
NETPATH
REACTOME
Association of TriC/CCT with target proteins during biosynthesis pathway
Protein folding pathway
Chaperonin-mediated protein folding pathway
Metabolism of proteins pathway
KEGG
INOH
PID NCI
Cross-References
SwissProt
TrEMBL
UniProt Splice Variant
Entrez Gene
UniGene
RefSeq NM_032301
HUGO
OMIM
CCDS CCDS12278
HPRD 12361
IMGT
EMBL
GenPept
RNA Seq Atlas