Version 5.4
Homo sapiens Gene: FMNL3
Summary
InnateDB Gene IDBG-31836.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol FMNL3
Gene Name formin-like 3
Synonyms
Species Homo sapiens
Ensembl Gene ENSG00000161791
Encoded Proteins
IDBP-31838
formin-like 3
IDBP-31840
formin-like 3
IDBP-595645
formin-like 3
IDBP-601496
formin-like 3
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary The protein encoded by this gene contains a formin homology 2 domain and has high sequence identity to the mouse Wbp3 protein. Two alternative transcripts encoding different isoforms have been described. [provided by RefSeq, Jul 2008]
Gene Information
Type Protein coding
Genomic Location Chromosome 12:49636499-49708165
Strand Reverse strand
Band q13.12
Transcripts
ENST00000335154 ENSP00000335655
ENST00000352151 ENSP00000344311
ENST00000550668
ENST00000550488 ENSP00000447479
ENST00000549137
ENST00000550970
ENST00000550424 ENSP00000448939
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 9 experimentally validated interaction(s) in this database.
Experimentally validated
Total 9 [view]
Protein-Protein 9 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Gene Ontology

Molecular Function
Accession GO Term
GO:0003779 actin binding
GO:0005488 binding
GO:0005515 protein binding
GO:0017048 Rho GTPase binding
GO:0032794 GTPase activating protein binding
Biological Process
GO:0007010 cytoskeleton organization
GO:0008360 regulation of cell shape
GO:0016043 cellular component organization
GO:0016477 cell migration
GO:0030036 actin cytoskeleton organization
Cellular Component
GO:0005737 cytoplasm
Orthologs
Species
Mus musculus
Bos taurus
Gene ID
Gene Order
ENSMUSG00000023008
View Gene Order
ENSBTAG00000016593
Not yet available
Cross-References
SwissProt Q8IVF7
TrEMBL
UniProt Splice Variant
Entrez Gene 91010
UniGene Hs.179838 Hs.33104 Hs.657959 Hs.708422
RefSeq NM_198900 NM_175736 XM_005269218 XM_005269219
HUGO HGNC:23698
OMIM
CCDS CCDS41780 CCDS44874
HPRD 17007
IMGT
EMBL AB095934 AC020612 AK128195 BC159100
GenPept AAI59101 BAC23110 BAC87319
RNA Seq Atlas 91010

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca