Version 5.4
Homo sapiens Gene: ZAN
Summary
InnateDB Gene IDBG-31977.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol ZAN
Gene Name zonadhesin
Synonyms
Species Homo sapiens
Ensembl Gene ENSG00000146839
Encoded Proteins
IDBP-585382
zonadhesin
IDBP-593060
zonadhesin
IDBP-589037
zonadhesin
IDBP-596423
zonadhesin
IDBP-809319
zonadhesin (gene/pseudogene)
IDBP-809331
zonadhesin (gene/pseudogene)
IDBP-809333
zonadhesin (gene/pseudogene)
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene encodes a sperm membrane protein that binds the zona pellucida of the egg in a species-specific manner. The encoded protein may be involved in signaling or gamete recognition. Alternate transcriptional splice variants, encoding different isoforms, have been characterized. [provided by RefSeq, Jul 2008]
This gene encodes a protein that functions in the species specificity of sperm adhesion to the egg zona pellucida. The encoded protein is located in the acrosome and may be involved in signaling or gamete recognition. Alternative splicing of this gene results in multiple transcript variants. [provided by RefSeq, Mar 2014]
Gene Information
Type Protein coding
Genomic Location Chromosome 7:100733626-100797797
Strand Forward strand
Band q22.1
Transcripts
ENST00000546292 ENSP00000445943
ENST00000538115 ENSP00000445091
ENST00000542585 ENSP00000444427
ENST00000546213 ENSP00000441117
ENST00000613979 ENSP00000480750
ENST00000620868
ENST00000620596 ENSP00000481742
ENST00000618565 ENSP00000478371
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 1 experimentally validated interaction(s) in this database.
Experimentally validated
Total 1 [view]
Protein-Protein 0
Protein-DNA 1 [view]
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Gene Ontology

Molecular Function
Accession GO Term
GO:0005515 protein binding
Biological Process
Cellular Component
GO:0016020 membrane
Orthologs
Species
Mus musculus
Bos taurus
Gene ID
Gene Order
ENSMUSG00000079173
View Gene Order
ENSBTAG00000003432
Not yet available
Cross-References
SwissProt
TrEMBL
UniProt Splice Variant
Entrez Gene
UniGene Hs.307004
RefSeq NM_003386 NM_173059
HUGO
OMIM
CCDS
HPRD 03846
IMGT
EMBL
GenPept
RNA Seq Atlas

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca