InnateDB: Systems Biology of the Innate Immune Response

Homo sapiens Gene: RPS23

Summary

InnateDB Gene

IDBG-32148.6

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

RPS23

Gene Name

ribosomal protein S23

Synonyms

S23

Species

Homo sapiens

Ensembl Gene

ENSG00000186468

Encoded Proteins

IDBP-32150

ribosomal protein S23

IDBP-480155

ribosomal protein S23

IDBP-478609

ribosomal protein S23

IDBP-481597

ribosomal protein S23

IDBP-475528

ribosomal protein S23

IDBP-474286

ribosomal protein S23

Protein Structure

Useful resources

Stemformatics EHFPI ImmGen

Entrez Gene

Summary

Ribosomes, the organelles that catalyze protein synthesis, consist of a small 40S subunit and a large 60S subunit. Together these subunits are composed of 4 RNA species and approximately 80 structurally distinct proteins. This gene encodes a ribosomal protein that is a component of the 40S subunit. The protein belongs to the S12P family of ribosomal proteins. It is located in the cytoplasm. The protein shares significant amino acid similarity with S. cerevisiae ribosomal protein S28. As is typical for genes encoding ribosomal proteins, there are multiple processed pseudogenes of this gene dispersed through the genome. [provided by RefSeq, Jul 2008]

Gene Information

Type

Protein coding

Genomic Location

Chromosome 5:82273358-82278577

Strand

Reverse strand

Band

q14.2

Transcripts

ENST00000296674	ENSP00000296674
ENST00000510210	ENSP00000427043
ENST00000512493	ENSP00000425865
ENST00000510019	ENSP00000425833
ENST00000507980	ENSP00000422071
ENST00000504293
ENST00000503605
ENST00000511844	ENSP00000420900

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 135 experimentally validated interaction(s) in this database.

Experimentally validated
Total	135 [view]
Protein-Protein	135 [view]
Protein-DNA	0
Protein-RNA	0
DNA-DNA	0
RNA-RNA	0
DNA-RNA	0

Gene Ontology

Molecular Function

Accession	GO Term
GO:0003735	structural constituent of ribosome
GO:0005515	protein binding
GO:0044822	poly(A) RNA binding

Biological Process

GO:0000184	nuclear-transcribed mRNA catabolic process, nonsense-mediated decay
GO:0006412	translation
GO:0006413	translational initiation
GO:0006414	translational elongation
GO:0006415	translational termination
GO:0006614	SRP-dependent cotranslational protein targeting to membrane
GO:0010467	gene expression
GO:0016032	viral process
GO:0016070	RNA metabolic process
GO:0016071	mRNA metabolic process
GO:0019058	viral life cycle
GO:0019083	viral transcription
GO:0044267	cellular protein metabolic process

Cellular Component

GO:0005622	intracellular
GO:0005730	nucleolus
GO:0005737	cytoplasm
GO:0005829	cytosol
GO:0005840	ribosome
GO:0015935	small ribosomal subunit
GO:0016020	membrane
GO:0022627	cytosolic small ribosomal subunit