Version 5.4
Homo sapiens Gene: DSCR4
Summary
InnateDB Gene IDBG-3221.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol DSCR4
Gene Name Down syndrome critical region gene 4
Synonyms DCRB; DSCRB
Species Homo sapiens
Ensembl Gene ENSG00000184029
Encoded Proteins
IDBP-3223
Down syndrome critical region gene 4
IDBP-231848
Down syndrome critical region gene 4
IDBP-592181
Down syndrome critical region gene 4
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary The region of chromosome 21 between genes CBR and ERG (CBR-ERG region), which spans 2.5 Mb on 21q22.2, has been defined by analysis of patients with partial trisomy 21. It contributes significantly to the pathogenesis of many characteristics of Down syndrome, including morphological features, hypotonia, and mental retardation. This gene is found in this region and multiple transcripts may exist. It is mainly expressed in the placenta. [provided by RefSeq, Jul 2008]
Gene Information
Type Protein coding
Genomic Location Chromosome 21:37951425-38121360
Strand Reverse strand
Band q22.13
Transcripts
ENST00000328264 ENSP00000328676
ENST00000398948 ENSP00000381921
ENST00000482032 ENSP00000434191
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
Gene Ontology

Molecular Function
Accession GO Term
GO:0003674 molecular_function
Biological Process
GO:0008150 biological_process
Cellular Component
GO:0005575 cellular_component
Orthologs
No orthologs found for this gene
Cross-References
SwissProt
TrEMBL
UniProt Splice Variant
Entrez Gene
UniGene Hs.23251 Hs.580861
RefSeq NM_005867
HUGO
OMIM
CCDS CCDS33554
HPRD 05318
IMGT
EMBL
GenPept
RNA Seq Atlas

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca