InnateDB: Systems Biology of the Innate Immune Response

Homo sapiens Gene: RHOB

Summary

InnateDB Gene

IDBG-32465.7

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

RHOB

Gene Name

ras homolog family member B

Synonyms

ARH6; ARHB; MST081; MSTP081; RHOH6

Species

Homo sapiens

Ensembl Gene

ENSG00000143878

Encoded Proteins

IDBP-32469

ras homolog gene family, member B

Protein Structure

Useful resources

Stemformatics EHFPI ImmGen

Entrez Gene

Summary

Currently no Entrez Summary Available. You might want to check the Summary Sections of the Orthologs.

Gene Information

Type

Protein coding

Genomic Location

Chromosome 2:20447074-20449445

Strand

Forward strand

Band

p24.1

Transcripts

ENST00000272233

ENSP00000272233

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 35 experimentally validated interaction(s) in this database.
They are also associated with 3 interaction(s) predicted by orthology.

Experimentally validated
Total	35 [view]
Protein-Protein	34 [view]
Protein-DNA	1 [view]
Protein-RNA	0
DNA-DNA	0
RNA-RNA	0
DNA-RNA	0

Predicted by orthology
Total	3 [view]

Gene Ontology

Molecular Function

Accession	GO Term
GO:0003924	GTPase activity
GO:0005515	protein binding
GO:0005525	GTP binding
GO:0019003	GDP binding

Biological Process

GO:0000910	cytokinesis
GO:0001525	angiogenesis
GO:0006184	GTP catabolic process
GO:0006915	apoptotic process
GO:0006927	transformed cell apoptotic process
GO:0007155	cell adhesion
GO:0007165	signal transduction
GO:0007264	small GTPase mediated signal transduction
GO:0007266	Rho protein signal transduction
GO:0007411	axon guidance
GO:0007596	blood coagulation
GO:0008333	endosome to lysosome transport
GO:0015031	protein transport
GO:0030168	platelet activation
GO:0043065	positive regulation of apoptotic process
GO:0045766	positive regulation of angiogenesis
GO:0045786	negative regulation of cell cycle
GO:0051056	regulation of small GTPase mediated signal transduction
GO:0070301	cellular response to hydrogen peroxide
GO:0071479	cellular response to ionizing radiation

Cellular Component

GO:0005622	intracellular
GO:0005634	nucleus
GO:0005829	cytosol
GO:0005886	plasma membrane
GO:0010008	endosome membrane
GO:0016020	membrane
GO:0031902	late endosome membrane
GO:0032154	cleavage furrow
GO:0070062	extracellular vesicular exosome