Homo sapiens Gene: UFSP1
Summary
InnateDB Gene IDBG-32493.5
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol UFSP1
Gene Name UFM1-specific peptidase 1 (non-functional)
Synonyms
Species Homo sapiens
Ensembl Gene ENSG00000176125
Encoded Proteins
UFM1-specific peptidase 1 (non-functional)
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene encodes a protein that is similar to other Ufm1-specific proteases. Studies in mouse determined that Ufsp1 releases Ufm1 (ubiquitin-fold modifier 1) from its bound conjugated complexes which also makes it into an active form. Because the human UFSP1 protein is shorter on the N-terminus and lacks a conserved Cys active site, it is predicted to be non-functional.[provided by RefSeq, Nov 2009]
Gene Information
Type Protein coding
Genomic Location Chromosome 7:100888723-100889718
Strand Reverse strand
Band q22.1
Transcripts
ENST00000388761 ENSP00000373413
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
Gene Ontology

Molecular Function
Accession GO Term
GO:0003674 molecular_function
GO:0016790 thiolester hydrolase activity
GO:0071567 UFM1 hydrolase activity
Biological Process
GO:0008150 biological_process
Cellular Component
GO:0070062 extracellular vesicular exosome
Orthologs
Species
Mus musculus
Bos taurus
Gene ID
Gene Order
Not yet available
Cross-References
SwissProt
TrEMBL
UniProt Splice Variant
Entrez Gene
UniGene Hs.534845
RefSeq NM_001015072
HUGO
OMIM
CCDS CCDS34710
HPRD 18630
IMGT
EMBL
GenPept
RNA Seq Atlas