Version 5.4
Homo sapiens Gene: CSRNP2
Summary
InnateDB Gene IDBG-33094.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol CSRNP2
Gene Name cysteine-serine-rich nuclear protein 2
Synonyms
Species Homo sapiens
Ensembl Gene ENSG00000110925
Encoded Proteins
IDBP-33096
cysteine-serine-rich nuclear protein 2
IDBP-595274
cysteine-serine-rich nuclear protein 2
IDBP-599250
cysteine-serine-rich nuclear protein 2
IDBP-595395
cysteine-serine-rich nuclear protein 2
IDBP-598815
cysteine-serine-rich nuclear protein 2
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary The protein encoded by this gene belongs to the CSRNP family of nuclear proteins that share conserved regions, including cysteine- and serine- rich regions, a basic domain, a transcriptional activation domain, and bind the sequence 'AGAGTG', thus have the hallmark of transcription factors. Studies in mice suggest that these genes may have redundant functions. Alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, Aug 2011]
Gene Information
Type Protein coding
Genomic Location Chromosome 12:51061205-51083664
Strand Reverse strand
Band q13.12
Transcripts
ENST00000228515 ENSP00000228515
ENST00000548206 ENSP00000447983
ENST00000548981 ENSP00000447657
ENST00000550533
ENST00000552899 ENSP00000447065
ENST00000546935 ENSP00000449152
ENST00000552680
ENST00000550461
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 2 experimentally validated interaction(s) in this database.
Experimentally validated
Total 2 [view]
Protein-Protein 2 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Gene Ontology

Molecular Function
Accession GO Term
GO:0001228 RNA polymerase II transcription regulatory region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription
GO:0003700 sequence-specific DNA binding transcription factor activity
GO:0005515 protein binding
GO:0019902 phosphatase binding
GO:0043565 sequence-specific DNA binding
Biological Process
GO:0006351 transcription, DNA-templated
GO:0006915 apoptotic process
GO:0010923 negative regulation of phosphatase activity
GO:0045944 positive regulation of transcription from RNA polymerase II promoter
Cellular Component
GO:0005634 nucleus
Orthologs
Species
Mus musculus
Bos taurus
Gene ID
Gene Order
ENSMUSG00000044636
View Gene Order
ENSBTAG00000010928
Not yet available
Cross-References
SwissProt
TrEMBL
UniProt Splice Variant
Entrez Gene
UniGene Hs.524425 Hs.665681 Hs.708934 Hs.735205
RefSeq NM_030809 XM_006719621
HUGO
OMIM
CCDS CCDS8807
HPRD 12608
IMGT
EMBL
GenPept
RNA Seq Atlas

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca