Version 5.4
Homo sapiens Gene: CIAPIN1
Summary
InnateDB Gene IDBG-33248.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol CIAPIN1
Gene Name cytokine induced apoptosis inhibitor 1
Synonyms
Species Homo sapiens
Ensembl Gene ENSG00000005194
Encoded Proteins
IDBP-241670
cytokine induced apoptosis inhibitor 1
IDBP-751190
IDBP-747970
IDBP-753637
IDBP-746480
IDBP-747956
IDBP-750409
IDBP-754389
IDBP-752225
IDBP-750970
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary CIAPIN1 is a cytokine-induced inhibitor of apoptosis with no relation to apoptosis regulatory molecules of the BCL2 (MIM 151430) or CASP (see MIM 147678) families. Expression of CIAPIN1 is dependent on growth factor stimulation (Shibayama et al., 2004 [PubMed 14970183]).[supplied by OMIM, Mar 2008]
Gene Information
Type Protein coding
Genomic Location Chromosome 16:57428169-57447528
Strand Reverse strand
Band q21
Transcripts
ENST00000394391 ENSP00000377914
ENST00000570000 ENSP00000457622
ENST00000564885
ENST00000569370 ENSP00000457042
ENST00000563341 ENSP00000455572
ENST00000567518 ENSP00000456114
ENST00000565368
ENST00000565961 ENSP00000455309
ENST00000563561
ENST00000567751 ENSP00000457400
ENST00000566284
ENST00000569979 ENSP00000458000
ENST00000565786 ENSP00000457318
ENST00000569246
ENST00000568940 ENSP00000454480
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 18 experimentally validated interaction(s) in this database.
They are also associated with 1 interaction(s) predicted by orthology.
Experimentally validated
Total 18 [view]
Protein-Protein 17 [view]
Protein-DNA 1 [view]
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 1 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0005515 protein binding
GO:0008168 methyltransferase activity
GO:0009055 electron carrier activity
GO:0046872 metal ion binding
GO:0051536 iron-sulfur cluster binding
GO:0051537 2 iron, 2 sulfur cluster binding
Biological Process
GO:0006915 apoptotic process
GO:0008152 metabolic process
GO:0016226 iron-sulfur cluster assembly
GO:0030097 hemopoiesis
GO:0032259 methylation
GO:0043066 negative regulation of apoptotic process
GO:0044281 small molecule metabolic process
Cellular Component
GO:0005634 nucleus
GO:0005730 nucleolus
GO:0005737 cytoplasm
GO:0005739 mitochondrion
GO:0005758 mitochondrial intermembrane space
Orthologs
Species
Mus musculus
Bos taurus
Gene ID
Gene Order
ENSMUSG00000031781
View Gene Order
ENSBTAG00000001854
Not yet available
Pathways
NETPATH
REACTOME
REACT_160176
Cytosolic iron-sulfur cluster assembly pathway
REACT_111217
Metabolism pathway
KEGG
INOH
PID NCI
Cross-References
SwissProt
TrEMBL H3BTT4 H3BTZ8
UniProt Splice Variant
Entrez Gene 57019
UniGene Hs.4900
RefSeq NM_020313 XM_005256061 XM_005256062
HUGO HGNC:28050
OMIM 608943
CCDS CCDS10781
HPRD 12338
IMGT
EMBL AC009052
GenPept
RNA Seq Atlas 57019

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca