Version 5.4
Homo sapiens Gene: DRG2
Summary
InnateDB Gene IDBG-33501.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol DRG2
Gene Name developmentally regulated GTP binding protein 2
Synonyms
Species Homo sapiens
Ensembl Gene ENSG00000108591
Encoded Proteins
IDBP-33503
developmentally regulated GTP binding protein 2
IDBP-238964
developmentally regulated GTP binding protein 2
IDBP-760608
IDBP-760748
IDBP-760317
IDBP-760294
IDBP-763455
IDBP-762262
IDBP-763833
IDBP-761040
IDBP-763661
IDBP-758406
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene encodes a GTP-binding protein known to function in the regulation of cell growth and differentiation. Read-through transcripts containing this gene and a downstream gene have been identified, but they are not thought to encode a fusion protein. This gene is located within the Smith-Magenis syndrome region on chromosome 17. [provided by RefSeq, Jan 2012]
Gene Information
Type Protein coding
Genomic Location Chromosome 17:18087886-18107971
Strand Forward strand
Band p11.2
Transcripts
ENST00000225729 ENSP00000225729
ENST00000395726 ENSP00000379076
ENST00000473213
ENST00000467099 ENSP00000463522
ENST00000496428 ENSP00000462978
ENST00000497744
ENST00000482564
ENST00000580929 ENSP00000462060
ENST00000577771
ENST00000579224 ENSP00000464244
ENST00000582419 ENSP00000463747
ENST00000582528
ENST00000584212
ENST00000578767
ENST00000578173
ENST00000582314 ENSP00000464004
ENST00000577450 ENSP00000463436
ENST00000579601 ENSP00000464076
ENST00000583162
ENST00000583355 ENSP00000463256
ENST00000580055 ENSP00000463268
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 11 experimentally validated interaction(s) in this database.
They are also associated with 1 interaction(s) predicted by orthology.
Experimentally validated
Total 11 [view]
Protein-Protein 11 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 1 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0005525 GTP binding
GO:0015093 ferrous iron transmembrane transporter activity
Biological Process
GO:0007165 signal transduction
GO:0015684 ferrous iron transport
Cellular Component
GO:0005737 cytoplasm
GO:0005739 mitochondrion
GO:0016020 membrane
GO:0016021 integral component of membrane
Orthologs
Species
Mus musculus
Bos taurus
Gene ID
Gene Order
ENSMUSG00000020537
View Gene Order
ENSBTAG00000006517
Not yet available
Cross-References
SwissProt
TrEMBL
UniProt Splice Variant
Entrez Gene
UniGene Hs.78582
RefSeq NM_001388 XM_006721468
HUGO
OMIM
CCDS CCDS11191
HPRD 04286
IMGT
EMBL
GenPept
RNA Seq Atlas

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca