Version 5.4
Homo sapiens Gene: FBXL13
Summary
InnateDB Gene IDBG-33935.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol FBXL13
Gene Name F-box and leucine-rich repeat protein 13
Synonyms
Species Homo sapiens
Ensembl Gene ENSG00000161040
Encoded Proteins
IDBP-33937
F-box and leucine-rich repeat protein 13
IDBP-33941
F-box and leucine-rich repeat protein 13
IDBP-33945
F-box and leucine-rich repeat protein 13
IDBP-384440
F-box and leucine-rich repeat protein 13
IDBP-384445
F-box and leucine-rich repeat protein 13
IDBP-384446
F-box and leucine-rich repeat protein 13
IDBP-384447
F-box and leucine-rich repeat protein 13
IDBP-384449
F-box and leucine-rich repeat protein 13
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary Members of the F-box protein family, such as FBXL13, are characterized by an approximately 40-amino acid F-box motif. SCF complexes, formed by SKP1 (MIM 601434), cullin (see CUL1; MIM 603134), and F-box proteins, act as protein-ubiquitin ligases. F-box proteins interact with SKP1 through the F box, and they interact with ubiquitination targets through other protein interaction domains (Jin et al., 2004 [PubMed 15520277]).[supplied by OMIM, Mar 2008]
Gene Information
Type Protein coding
Genomic Location Chromosome 7:102813230-103074843
Strand Reverse strand
Band q22.1
Transcripts
ENST00000313221 ENSP00000321927
ENST00000379308 ENSP00000368610
ENST00000379305 ENSP00000368607
ENST00000455112 ENSP00000391550
ENST00000448002 ENSP00000405434
ENST00000456695 ENSP00000409716
ENST00000436908 ENSP00000388608
ENST00000440067 ENSP00000390126
ENST00000480422
ENST00000477915
ENST00000468216
ENST00000471074
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 3 experimentally validated interaction(s) in this database.
They are also associated with 1 interaction(s) predicted by orthology.
Experimentally validated
Total 3 [view]
Protein-Protein 3 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 1 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0005515 protein binding
Biological Process
Cellular Component
Orthologs
Species
Mus musculus
Bos taurus
Gene ID
Gene Order
ENSMUSG00000048520
View Gene Order
ENSBTAG00000016324
Not yet available
Cross-References
SwissProt
TrEMBL
UniProt Splice Variant
Entrez Gene
UniGene Hs.660029
RefSeq NM_001111038 NM_001287150 NM_145032 XM_005250208 XM_005250209 XM_005250212 XM_005250213 XM_006715897 XM_006715898
HUGO
OMIM
CCDS CCDS47678 CCDS5726 CCDS75649
HPRD 12364
IMGT
EMBL
GenPept
RNA Seq Atlas

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca