Homo sapiens Gene: FBXW10
Summary
InnateDB Gene IDBG-34276.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol FBXW10
Gene Name F-box and WD repeat domain containing 10
Synonyms Fbw10; HREP; SM25H2; SM2SH2
Species Homo sapiens
Ensembl Gene ENSG00000171931
Encoded Proteins
F-box and WD repeat domain containing 10
F-box and WD repeat domain containing 10
F-box and WD repeat domain containing 10
F-box and WD repeat domain containing 10
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary Members of the F-box protein family, such as FBXW10, are characterized by an approximately 40-amino acid F-box motif. SCF complexes, formed by SKP1 (MIM 601434), cullin (see CUL1; MIM 603134), and F-box proteins, act as protein-ubiquitin ligases. F-box proteins interact with SKP1 through the F box, and they interact with ubiquitination targets through other protein interaction domains (Jin et al., 2004 [PubMed 15520277]).[supplied by OMIM, Mar 2008]
Gene Information
Type Protein coding
Genomic Location Chromosome 17:18744024-18779349
Strand Forward strand
Band p11.2
Transcripts
ENST00000301938 ENSP00000306937
ENST00000308799 ENSP00000310382
ENST00000395667 ENSP00000379026
ENST00000395665 ENSP00000379025
ENST00000574478 ENSP00000463552
ENST00000573605
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 1 experimentally validated interaction(s) in this database.
Experimentally validated
Total 1 [view]
Protein-Protein 1 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Gene Ontology

Molecular Function
Accession GO Term
GO:0005515 protein binding
Biological Process
Cellular Component
Orthologs
Species
Mus musculus
Gene ID
Gene Order
Pathways
NETPATH
REACTOME
Association of TriC/CCT with target proteins during biosynthesis pathway
Protein folding pathway
Chaperonin-mediated protein folding pathway
Metabolism of proteins pathway
KEGG
INOH
PID NCI
Cross-References
SwissProt
TrEMBL
UniProt Splice Variant
Entrez Gene
UniGene Hs.592128
RefSeq NM_001267585 NM_001267586 XM_003846595 XM_006721420 XM_006721422 NM_001282540 NM_006382
HUGO
OMIM
CCDS CCDS11199 CCDS58524 CCDS45619 CCDS73996
HPRD 06851
IMGT
EMBL
GenPept
RNA Seq Atlas