Version 5.4
Homo sapiens Gene: DHRS4L2
Summary
InnateDB Gene IDBG-3441.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol DHRS4L2
Gene Name dehydrogenase/reductase (SDR family) member 4 like 2
Synonyms CR; NRDR; PHCR; PSCD; SCAD-SRL; SDR-SRL; SDR25C1; SDR25C2
Species Homo sapiens
Ensembl Gene ENSG00000187630
Encoded Proteins
IDBP-3443
dehydrogenase/reductase (SDR family) member 4 like 2
IDBP-3445
dehydrogenase/reductase (SDR family) member 4 like 2
IDBP-236167
dehydrogenase/reductase (SDR family) member 4 like 2
IDBP-599940
dehydrogenase/reductase (SDR family) member 4 like 2
IDBP-599434
dehydrogenase/reductase (SDR family) member 4 like 2
IDBP-595206
dehydrogenase/reductase (SDR family) member 4 like 2
IDBP-602651
dehydrogenase/reductase (SDR family) member 4 like 2
IDBP-594042
dehydrogenase/reductase (SDR family) member 4 like 2
IDBP-586967
dehydrogenase/reductase (SDR family) member 4 like 2
IDBP-589709
dehydrogenase/reductase (SDR family) member 4 like 2
IDBP-594387
dehydrogenase/reductase (SDR family) member 4 like 2
IDBP-810378
dehydrogenase/reductase (SDR family) member 4 like 2
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene encodes a member of the short chain dehydrogenase reductase family. The encoded protein may be an NADPH dependent retinol oxidoreductase. Alternate splicing results in multiple transcript variants. [provided by RefSeq, Aug 2010]
Gene Information
Type Protein coding
Genomic Location Chromosome 14:23969874-24006408
Strand Forward strand
Band q11.2
Transcripts
ENST00000335125 ENSP00000334801
ENST00000382755 ENSP00000372203
ENST00000397071 ENSP00000380261
ENST00000559411 ENSP00000453889
ENST00000558753 ENSP00000453845
ENST00000537912 ENSP00000439942
ENST00000559387 ENSP00000453173
ENST00000557812
ENST00000560276 ENSP00000452875
ENST00000545240 ENSP00000437883
ENST00000543805 ENSP00000441433
ENST00000534993 ENSP00000441095
ENST00000621761 ENSP00000481066
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 1 experimentally validated interaction(s) in this database.
Experimentally validated
Total 1 [view]
Protein-Protein 1 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Gene Ontology

Molecular Function
Accession GO Term
GO:0016491 oxidoreductase activity
Biological Process
GO:0008152 metabolic process
GO:0055114 oxidation-reduction process
Cellular Component
GO:0005576 extracellular region
Orthologs
No orthologs found for this gene
Pathways
NETPATH
REACTOME
KEGG
hsa00830
Retinol metabolism pathway
hsa04146
Peroxisome pathway
INOH
PID NCI
Cross-References
SwissProt
TrEMBL
UniProt Splice Variant
Entrez Gene
UniGene
RefSeq NM_001193635 NM_001193636 NM_001193637 NM_198083
HUGO
OMIM
CCDS CCDS73621 CCDS9606
HPRD 10880
IMGT
EMBL
GenPept
RNA Seq Atlas

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca