Version 5.4
Homo sapiens Gene: ALPK1
Summary
InnateDB Gene IDBG-34471.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol ALPK1
Gene Name alpha-kinase 1
Synonyms
Species Homo sapiens
Ensembl Gene ENSG00000073331
Encoded Proteins
IDBP-34473
alpha-kinase 1
IDBP-376060
alpha-kinase 1
IDBP-475936
alpha-kinase 1
IDBP-484232
alpha-kinase 1
IDBP-484772
alpha-kinase 1
IDBP-480352
alpha-kinase 1
IDBP-476854
alpha-kinase 1
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene encodes an alpha kinase. Mice which were homozygous for disrupted copies of this gene exhibited coordination defects (PMID: 21208416). Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Dec 2011]
Gene Information
Type Protein coding
Genomic Location Chromosome 4:112285509-112442620
Strand Forward strand
Band q25
Transcripts
ENST00000177648 ENSP00000177648
ENST00000426472
ENST00000458497 ENSP00000398048
ENST00000514594
ENST00000505176
ENST00000502366
ENST00000509722 ENSP00000424492
ENST00000505127 ENSP00000425559
ENST00000504488
ENST00000509688
ENST00000515330 ENSP00000423978
ENST00000515106 ENSP00000425273
ENST00000504745
ENST00000505912
ENST00000509209
ENST00000508589
ENST00000512847
ENST00000504176 ENSP00000426044
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 2 experimentally validated interaction(s) in this database.
Experimentally validated
Total 2 [view]
Protein-Protein 1 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 1 [view]
RNA-RNA 0
DNA-RNA 0
Gene Ontology

Molecular Function
Accession GO Term
GO:0004674 protein serine/threonine kinase activity
GO:0005524 ATP binding
GO:0016301 kinase activity
GO:0016772 transferase activity, transferring phosphorus-containing groups
Biological Process
GO:0006468 protein phosphorylation
GO:0016310 phosphorylation
Cellular Component
Orthologs
Species
Mus musculus
Bos taurus
Gene ID
Gene Order
ENSMUSG00000028028
View Gene Order
ENSBTAG00000034875
Not yet available
Cross-References
SwissProt
TrEMBL
UniProt Splice Variant
Entrez Gene
UniGene Hs.652825
RefSeq NM_001102406 NM_001253884 NM_025144 XM_005263245 XM_005263246 XM_005263247 XM_005263248
HUGO
OMIM
CCDS CCDS3697 CCDS58923
HPRD 09554
IMGT
EMBL
GenPept
RNA Seq Atlas

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca