InnateDB: Systems Biology of the Innate Immune Response

Homo sapiens Gene: SEC24D

Summary

InnateDB Gene

IDBG-35522.6

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

SEC24D

Gene Name

SEC24 family, member D (S. cerevisiae)

Synonyms

Species

Homo sapiens

Ensembl Gene

ENSG00000150961

Encoded Proteins

IDBP-35526

SEC24 family, member D (S. cerevisiae)

IDBP-376650

SEC24 family, member D (S. cerevisiae)

IDBP-475630

SEC24 family, member D (S. cerevisiae)

IDBP-475837

SEC24 family, member D (S. cerevisiae)

IDBP-482712

SEC24 family, member D (S. cerevisiae)

IDBP-483415

SEC24 family, member D (S. cerevisiae)

IDBP-474377

SEC24 family, member D (S. cerevisiae)

Protein Structure

Useful resources

Stemformatics EHFPI ImmGen

Entrez Gene

Summary

The protein encoded by this gene is a member of the SEC24 subfamily of the SEC23/SEC24 family, which is involved in vesicle trafficking. The encoded protein has similarity to yeast Sec24p component of COPII. COPII is the coat protein complex responsible for vesicle budding from the ER. This gene product is implicated in the shaping of the vesicle, and also in cargo selection and concentration. [provided by RefSeq, Jul 2008]

Gene Information

Type

Protein coding

Genomic Location

Chromosome 4:118722823-118838683

Strand

Reverse strand

Band

q26

Transcripts

ENST00000280551	ENSP00000280551
ENST00000419654	ENSP00000388324
ENST00000505134
ENST00000511481	ENSP00000425491
ENST00000502830
ENST00000511715
ENST00000514561	ENSP00000422717
ENST00000502526
ENST00000511033
ENST00000509818	ENSP00000424085
ENST00000514418
ENST00000506622	ENSP00000427249
ENST00000503683	ENSP00000426309
ENST00000505280

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 23 experimentally validated interaction(s) in this database.

Experimentally validated
Total	23 [view]
Protein-Protein	22 [view]
Protein-DNA	1 [view]
Protein-RNA	0
DNA-DNA	0
RNA-RNA	0
DNA-RNA	0

Gene Ontology

Molecular Function

Accession	GO Term
GO:0003674	molecular_function
GO:0008270	zinc ion binding

Biological Process

GO:0001701	in utero embryonic development
GO:0002474	antigen processing and presentation of peptide antigen via MHC class I
GO:0006886	intracellular protein transport
GO:0006888	ER to Golgi vesicle-mediated transport
GO:0018279	protein N-linked glycosylation via asparagine
GO:0019886	antigen processing and presentation of exogenous peptide antigen via MHC class II
GO:0043687	post-translational protein modification
GO:0044267	cellular protein metabolic process
GO:0044281	small molecule metabolic process
GO:0048208	COPII vesicle coating
GO:0061024	membrane organization

Cellular Component

GO:0000139	Golgi membrane
GO:0005789	endoplasmic reticulum membrane
GO:0005829	cytosol
GO:0012507	ER to Golgi transport vesicle membrane
GO:0030127	COPII vesicle coat
GO:0048471	perinuclear region of cytoplasm