Version 5.4
Homo sapiens Gene: RAB27B
Summary
InnateDB Gene IDBG-3593.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol RAB27B
Gene Name RAB27B, member RAS oncogene family
Synonyms C25KG
Species Homo sapiens
Ensembl Gene ENSG00000041353
Encoded Proteins
IDBP-3595
RAB27B, member RAS oncogene family
IDBP-726914
IDBP-727161
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary Members of the Rab protein family, including RAB27B, are prenylated, membrane-bound proteins involved in vesicular fusion and trafficking (Chen et al., 1997 [PubMed 9066979]).[supplied by OMIM, Nov 2010]
Gene Information
Type Protein coding
Genomic Location Chromosome 18:54717860-54895516
Strand Forward strand
Band q21.2
Transcripts
ENST00000262094 ENSP00000262094
ENST00000586570 ENSP00000468542
ENST00000586594
ENST00000592334 ENSP00000465009
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 10 experimentally validated interaction(s) in this database.
They are also associated with 2 interaction(s) predicted by orthology.
Experimentally validated
Total 10 [view]
Protein-Protein 10 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 2 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0003924 GTPase activity
GO:0005515 protein binding
GO:0005525 GTP binding
GO:0019003 GDP binding
GO:0019904 protein domain specific binding
Biological Process
GO:0006184 GTP catabolic process
GO:0006886 intracellular protein transport
GO:0006913 nucleocytoplasmic transport
GO:0007165 signal transduction
GO:0007264 small GTPase mediated signal transduction
GO:0015031 protein transport
GO:0017157 regulation of exocytosis
GO:0045921 positive regulation of exocytosis
GO:0071985 multivesicular body sorting pathway
Cellular Component
GO:0005622 intracellular
GO:0005794 Golgi apparatus
GO:0005795 Golgi stack
GO:0016020 membrane
GO:0016324 apical plasma membrane
GO:0030140 trans-Golgi network transport vesicle
GO:0030667 secretory granule membrane
GO:0032585 multivesicular body membrane
GO:0042589 zymogen granule membrane
GO:0070062 extracellular vesicular exosome
Orthologs
Species
Mus musculus
Bos taurus
Gene ID
Gene Order
ENSMUSG00000024511
View Gene Order
ENSBTAG00000002788
Not yet available
Pathways
NETPATH
REACTOME
KEGG
hsa04972
Pancreatic secretion pathway
INOH
PID NCI
Cross-References
SwissProt
TrEMBL
UniProt Splice Variant
Entrez Gene
UniGene Hs.25318 Hs.584795 Hs.664111
RefSeq NM_004163 XM_005266733 XM_005266734
HUGO
OMIM
CCDS CCDS11958
HPRD 04846
IMGT
EMBL
GenPept
RNA Seq Atlas

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca