Homo sapiens Gene: FBXL17
Summary
InnateDB Gene IDBG-36140.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol FBXL17
Gene Name F-box and leucine-rich repeat protein 17
Synonyms
Species Homo sapiens
Ensembl Gene ENSG00000145743
Encoded Proteins
F-box and leucine-rich repeat protein 17
F-box and leucine-rich repeat protein 17
F-box and leucine-rich repeat protein 17
F-box and leucine-rich repeat protein 17
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary Members of the F-box protein family, such as FBXL17, are characterized by an approximately 40-amino acid F-box motif. SCF complexes, formed by SKP1 (MIM 601434), cullin (see CUL1; MIM 603134), and F-box proteins, act as protein-ubiquitin ligases. F-box proteins interact with SKP1 through the F box, and they interact with ubiquitination targets through other protein interaction domains (Jin et al., 2004 [PubMed 15520277]).[supplied by OMIM, Mar 2008]
Gene Information
Type Protein coding
Genomic Location Chromosome 5:107859035-108382098
Strand Reverse strand
Band q21.3
Transcripts
ENST00000359660 ENSP00000352683
ENST00000496714 ENSP00000418111
ENST00000481160
ENST00000518486
ENST00000542267 ENSP00000437464
ENST00000619412 ENSP00000481439
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 10 experimentally validated interaction(s) in this database.
Experimentally validated
Total 10 [view]
Protein-Protein 9 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 1 [view]
RNA-RNA 0
DNA-RNA 0
Gene Ontology

Molecular Function
Accession GO Term
GO:0005515 protein binding
Biological Process
Cellular Component
Orthologs
Species
Mus musculus
Bos taurus
Gene ID
Gene Order
Not yet available
Cross-References
SwissProt
TrEMBL
UniProt Splice Variant
Entrez Gene
UniGene Hs.596830 Hs.657225 Hs.706199
RefSeq NM_001163315 XM_005272048
HUGO
OMIM
CCDS CCDS54886
HPRD 10950
IMGT
EMBL
GenPept
RNA Seq Atlas