Version 5.4
Homo sapiens Gene: IMMP1L
Summary
InnateDB Gene IDBG-37326.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol IMMP1L
Gene Name IMP1 inner mitochondrial membrane peptidase-like (S. cerevisiae)
Synonyms
Species Homo sapiens
Ensembl Gene ENSG00000148950
Encoded Proteins
IDBP-37328
IMP1 inner mitochondrial membrane peptidase-like (S. cerevisiae)
IDBP-594177
IMP1 inner mitochondrial membrane peptidase-like (S. cerevisiae)
IDBP-585265
IMP1 inner mitochondrial membrane peptidase-like (S. cerevisiae)
IDBP-589026
IMP1 inner mitochondrial membrane peptidase-like (S. cerevisiae)
IDBP-584495
IMP1 inner mitochondrial membrane peptidase-like (S. cerevisiae)
IDBP-592632
IMP1 inner mitochondrial membrane peptidase-like (S. cerevisiae)
IDBP-586812
IMP1 inner mitochondrial membrane peptidase-like (S. cerevisiae)
IDBP-599501
IMP1 inner mitochondrial membrane peptidase-like (S. cerevisiae)
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary The mitochondrial inner membrane peptidase (IMP) complex generates mature, active proteins in the mitochondrial intermembrane space by proteolytically removing the mitochondrial targeting presequence of nuclear-encoded proteins. IMP1 and IMP2 (IMMP2L; MIM 605977) are the catalytic subunits of the IMP complex (Burri et al., 2005 [PubMed 15814844]).[supplied by OMIM, Sep 2008]
Gene Information
Type Protein coding
Genomic Location Chromosome 11:31432401-31509645
Strand Reverse strand
Band p13
Transcripts
ENST00000278200 ENSP00000278200
ENST00000531331 ENSP00000432670
ENST00000532287 ENSP00000435576
ENST00000526776 ENSP00000434280
ENST00000534812 ENSP00000432673
ENST00000533512
ENST00000533642 ENSP00000432471
ENST00000527184
ENST00000528161
ENST00000532624
ENST00000529749 ENSP00000432001
ENST00000530023 ENSP00000432792
ENST00000531693
ENST00000532668
ENST00000533921
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
Gene Ontology

Molecular Function
Accession GO Term
GO:0003674 molecular_function
GO:0008236 serine-type peptidase activity
Biological Process
GO:0006508 proteolysis
GO:0006627 protein processing involved in protein targeting to mitochondrion
GO:0008150 biological_process
Cellular Component
GO:0005739 mitochondrion
GO:0016020 membrane
GO:0042720 mitochondrial inner membrane peptidase complex
Orthologs
Species
Mus musculus
Bos taurus
Gene ID
Gene Order
ENSMUSG00000042670
View Gene Order
ENSBTAG00000000475
Not yet available
Pathways
NETPATH
REACTOME
KEGG
hsa03060
Protein export pathway
INOH
PID NCI
Cross-References
SwissProt
TrEMBL
UniProt Splice Variant
Entrez Gene
UniGene Hs.502223
RefSeq NM_144981 XM_005252811 XM_005252814 XM_006718167 XM_006718168
HUGO
OMIM
CCDS CCDS7874
HPRD 08048
IMGT
EMBL
GenPept
RNA Seq Atlas

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca