Version 5.4
Homo sapiens Gene: DENND3
Summary
InnateDB Gene IDBG-37332.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol DENND3
Gene Name DENN/MADD domain containing 3
Synonyms
Species Homo sapiens
Ensembl Gene ENSG00000105339
Encoded Proteins
IDBP-37334
DENN/MADD domain containing 3
IDBP-377076
DENN/MADD domain containing 3
IDBP-479957
DENN/MADD domain containing 3
IDBP-477844
DENN/MADD domain containing 3
IDBP-480471
DENN/MADD domain containing 3
IDBP-478303
DENN/MADD domain containing 3
IDBP-479011
DENN/MADD domain containing 3
IDBP-485061
DENN/MADD domain containing 3
IDBP-477675
DENN/MADD domain containing 3
IDBP-481168
DENN/MADD domain containing 3
IDBP-475093
DENN/MADD domain containing 3
IDBP-475270
DENN/MADD domain containing 3
IDBP-481735
DENN/MADD domain containing 3
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary Currently no Entrez Summary Available. You might want to check the Summary Sections of the Orthologs.
Gene Information
Type Protein coding
Genomic Location Chromosome 8:141117278-141195808
Strand Forward strand
Band q24.3
Transcripts
ENST00000262585 ENSP00000262585
ENST00000424248 ENSP00000410594
ENST00000519291 ENSP00000430625
ENST00000518347 ENSP00000430695
ENST00000518198 ENSP00000428641
ENST00000519811 ENSP00000428714
ENST00000520986 ENSP00000429780
ENST00000523058 ENSP00000430786
ENST00000518668 ENSP00000428276
ENST00000518249 ENSP00000428155
ENST00000523015
ENST00000521477
ENST00000520482
ENST00000523066
ENST00000518806
ENST00000517985 ENSP00000429533
ENST00000517813
ENST00000523308 ENSP00000430912
ENST00000520571
ENST00000523530
ENST00000521835
ENST00000520725 ENSP00000429725
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 2 experimentally validated interaction(s) in this database.
Experimentally validated
Total 2 [view]
Protein-Protein 2 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Gene Ontology

Molecular Function
Accession GO Term
GO:0005515 protein binding
GO:0017112 Rab guanyl-nucleotide exchange factor activity
Biological Process
GO:0008333 endosome to lysosome transport
GO:0032313 regulation of Rab GTPase activity
GO:0032851 positive regulation of Rab GTPase activity
GO:0044257 cellular protein catabolic process
Cellular Component
Orthologs
Species
Mus musculus
Bos taurus
Gene ID
Gene Order
ENSMUSG00000036661
View Gene Order
ENSBTAG00000006132
Not yet available
Cross-References
SwissProt
TrEMBL
UniProt Splice Variant
Entrez Gene 22898
UniGene Hs.18166 Hs.714882 Hs.715168 Hs.715908
RefSeq NM_014957 XM_005250838 XM_005250839 XM_005250841 XM_005250843
HUGO HGNC:29134
OMIM
CCDS CCDS34947
HPRD 11114
IMGT
EMBL
GenPept
RNA Seq Atlas 22898

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca