Version 5.4
Homo sapiens Gene: INTU
Summary
InnateDB Gene IDBG-37381.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol INTU
Gene Name inturned planar cell polarity effector homolog (Drosophila)
Synonyms
Species Homo sapiens
Ensembl Gene ENSG00000164066
Encoded Proteins
IDBP-37383
inturned planar cell polarity effector homolog (Drosophila)
IDBP-474139
inturned planar cell polarity effector homolog (Drosophila)
IDBP-480143
inturned planar cell polarity effector homolog (Drosophila)
IDBP-484471
inturned planar cell polarity effector homolog (Drosophila)
IDBP-474619
inturned planar cell polarity effector homolog (Drosophila)
IDBP-474844
inturned planar cell polarity effector homolog (Drosophila)
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary Currently no Entrez Summary Available. You might want to check the Summary Sections of the Orthologs.
Gene Information
Type Protein coding
Genomic Location Chromosome 4:127623271-127726737
Strand Forward strand
Band q28.1
Transcripts
ENST00000335251 ENSP00000334003
ENST00000504491 ENSP00000422550
ENST00000503626 ENSP00000426287
ENST00000503952 ENSP00000421995
ENST00000504276
ENST00000506283 ENSP00000426171
ENST00000512995
ENST00000510766 ENSP00000427150
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
Gene Ontology

Molecular Function
Accession GO Term
GO:0005515 protein binding
Biological Process
GO:0007399 nervous system development
GO:0008589 regulation of smoothened signaling pathway
GO:0010839 negative regulation of keratinocyte proliferation
GO:0021513 spinal cord dorsal/ventral patterning
GO:0030216 keratinocyte differentiation
GO:0031069 hair follicle morphogenesis
GO:0042384 cilium assembly
GO:0045880 positive regulation of smoothened signaling pathway
GO:0051782 negative regulation of cell division
GO:0060173 limb development
GO:0060271 cilium morphogenesis
Cellular Component
GO:0005737 cytoplasm
GO:0009986 cell surface
Orthologs
Species
Mus musculus
Bos taurus
Gene ID
Gene Order
ENSMUSG00000060798
View Gene Order
ENSBTAG00000012824
Not yet available
Pathways
NETPATH
REACTOME
REACT_228134
Signaling by Hedgehog pathway
REACT_111102
Signal Transduction pathway
REACT_267634
Hedgehog 'off' state pathway
KEGG
INOH
PID NCI
Cross-References
SwissProt
TrEMBL
UniProt Splice Variant
Entrez Gene
UniGene Hs.391481
RefSeq NM_015693
HUGO
OMIM
CCDS CCDS34061
HPRD 15113
IMGT
EMBL
GenPept
RNA Seq Atlas

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca