Version 5.4
Homo sapiens Gene: ELL
Summary
InnateDB Gene IDBG-38288.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol ELL
Gene Name elongation factor RNA polymerase II
Synonyms C19orf17; ELL1; MEN; PPP1R68
Species Homo sapiens
Ensembl Gene ENSG00000105656
Encoded Proteins
IDBP-38290
elongation factor RNA polymerase II
IDBP-813085
elongation factor RNA polymerase II
IDBP-813084
elongation factor RNA polymerase II
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary Currently no Entrez Summary Available. You might want to check the Summary Sections of the Orthologs.
Gene Information
Type Protein coding
Genomic Location Chromosome 19:18442663-18522127
Strand Reverse strand
Band p13.11
Transcripts
ENST00000262809 ENSP00000262809
ENST00000596124 ENSP00000475648
ENST00000594635 ENSP00000475681
ENST00000596915
ENST00000610152
ENST00000608165
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 26 experimentally validated interaction(s) in this database.
They are also associated with 4 interaction(s) predicted by orthology.
Experimentally validated
Total 26 [view]
Protein-Protein 23 [view]
Protein-DNA 3 [view]
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 4 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0005515 protein binding
GO:0019902 phosphatase binding
Biological Process
GO:0001701 in utero embryonic development
GO:0006366 transcription from RNA polymerase II promoter
GO:0006368 transcription elongation from RNA polymerase II promoter
GO:0010467 gene expression
GO:0010923 negative regulation of phosphatase activity
GO:0016032 viral process
GO:0032786 positive regulation of DNA-templated transcription, elongation
GO:0050434 positive regulation of viral transcription
Cellular Component
GO:0005654 nucleoplasm
GO:0008023 transcription elongation factor complex
GO:0015030 Cajal body
GO:0016607 nuclear speck
Orthologs
Species
Mus musculus
Bos taurus
Gene ID
Gene Order
ENSMUSG00000070002
View Gene Order
ENSBTAG00000003587
Not yet available
Pathways
NETPATH
REACTOME
REACT_6344
Tat-mediated HIV elongation arrest and recovery pathway
REACT_6143
Pausing and recovery of Tat-mediated HIV elongation pathway
REACT_22107
RNA Polymerase II Pre-transcription Events pathway
REACT_1845
Formation of RNA Pol II elongation complex pathway
REACT_833
RNA Polymerase II Transcription Elongation pathway
REACT_22201
Formation of HIV elongation complex in the absence of HIV Tat pathway
REACT_6244
Pausing and recovery of HIV elongation pathway
REACT_6346
Formation of HIV-1 elongation complex containing HIV-1 Tat pathway
REACT_6162
Tat-mediated elongation of the HIV-1 transcript pathway
REACT_6259
HIV elongation arrest and recovery pathway
REACT_6233
Transcription of the HIV genome pathway
REACT_6361
Late Phase of HIV Life Cycle pathway
REACT_6274
HIV Transcription Elongation pathway
REACT_1366
RNA Polymerase II Transcription pathway
REACT_6256
HIV Life Cycle pathway
REACT_6185
HIV Infection pathway
REACT_71
Gene Expression pathway
REACT_116125
Disease pathway
KEGG
INOH
PID NCI
Cross-References
SwissProt
TrEMBL Q75MS0 U3KQA3
UniProt Splice Variant
Entrez Gene 8178
UniGene
RefSeq NM_006532
HUGO HGNC:23114
OMIM 600284
CCDS CCDS12380
HPRD
IMGT
EMBL AC005387 AC010335
GenPept AAC28752
RNA Seq Atlas 8178

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca