InnateDB: Systems Biology of the Innate Immune Response

Homo sapiens Gene: SLC52A3

Summary

InnateDB Gene

IDBG-38373.7

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

SLC52A3

Gene Name

solute carrier family 52, riboflavin transporter, member 3

Synonyms

Species

Homo sapiens

Ensembl Gene

ENSG00000101276

Encoded Proteins

IDBP-38375

chromosome 20 open reading frame 54

IDBP-38379

chromosome 20 open reading frame 54

Protein Structure

Useful resources

Stemformatics EHFPI ImmGen

Entrez Gene

Summary

This gene encodes a riboflavin transporter protein that is strongly expressed in the intestine and likely plays a role in intestinal absorption of riboflavin. The protein is predicted to have eleven transmembrane domains and a cell surface localization signal in the C-terminus. Mutations at this locus have been associated with Brown-Vialetto-Van Laere syndrome and Fazio-Londe disease. [provided by RefSeq, Mar 2012]

Gene Information

Type

Protein coding

Genomic Location

Chromosome 20:760080-768487

Strand

Reverse strand

Band

p13

Transcripts

ENST00000381944	ENSP00000371370
ENST00000217254	ENSP00000217254
ENST00000473664
ENST00000488495

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 1 interaction(s) predicted by orthology.

Predicted by orthology
Total	1 [view]

Gene Ontology

Molecular Function

Accession	GO Term
GO:0005515	protein binding
GO:0032217	riboflavin transporter activity

Biological Process

GO:0006766	vitamin metabolic process
GO:0006767	water-soluble vitamin metabolic process
GO:0006771	riboflavin metabolic process
GO:0007605	sensory perception of sound
GO:0032218	riboflavin transport
GO:0034605	cellular response to heat
GO:0044281	small molecule metabolic process