Version 5.4
Homo sapiens Gene: GSDMD
Summary
InnateDB Gene IDBG-38472.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol GSDMD
Gene Name gasdermin D
Synonyms
Species Homo sapiens
Ensembl Gene ENSG00000104518
Encoded Proteins
IDBP-38474
gasdermin D
IDBP-587881
gasdermin D
IDBP-599362
gasdermin D
IDBP-589084
gasdermin D
IDBP-601517
gasdermin D
IDBP-588556
gasdermin D
IDBP-584368
gasdermin D
IDBP-583362
gasdermin D
IDBP-599648
gasdermin D
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary Gasdermin D is a member of the gasdermin family. Members of this family appear to play a role in regulation of epithelial proliferation. Gasdermin D has been suggested to act as a tumor suppressor. Alternatively spliced transcript variants have been described. [provided by RefSeq, Oct 2009]
Gene Information
Type Protein coding
Genomic Location Chromosome 8:143553207-143563062
Strand Forward strand
Band q24.3
Transcripts
ENST00000262580 ENSP00000262580
ENST00000526406 ENSP00000433209
ENST00000529854 ENSP00000432351
ENST00000533348 ENSP00000434386
ENST00000533063 ENSP00000433958
ENST00000531184
ENST00000525721 ENSP00000434452
ENST00000534018 ENSP00000436684
ENST00000533888 ENSP00000437065
ENST00000524846
ENST00000528475
ENST00000526469
ENST00000526051
ENST00000534602
ENST00000531173
ENST00000525208 ENSP00000433263
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 1 experimentally validated interaction(s) in this database.
Experimentally validated
Total 1 [view]
Protein-Protein 1 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Gene Ontology

Molecular Function
Accession GO Term
Biological Process
GO:0031668 cellular response to extracellular stimulus
Cellular Component
Orthologs
Species
Mus musculus
Bos taurus
Gene ID
Gene Order
ENSMUSG00000022575
View Gene Order
ENSBTAG00000021474
Not yet available
Cross-References
SwissProt
TrEMBL E9PQ48 E9PRF1
UniProt Splice Variant
Entrez Gene 79792
UniGene Hs.118983
RefSeq NM_001166237 NM_024736
HUGO HGNC:25697
OMIM
CCDS CCDS34956
HPRD 11014
IMGT
EMBL AC067930
GenPept
RNA Seq Atlas 79792

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca