Version 5.4
Homo sapiens Gene: CRTC1
Summary
InnateDB Gene IDBG-38700.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol CRTC1
Gene Name CREB regulated transcription coactivator 1
Synonyms MECT1; TORC-1; TORC1; WAMTP1
Species Homo sapiens
Ensembl Gene ENSG00000105662
Encoded Proteins
IDBP-38702
CREB regulated transcription coactivator 1
IDBP-38704
CREB regulated transcription coactivator 1
IDBP-761695
IDBP-762036
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary Currently no Entrez Summary Available. You might want to check the Summary Sections of the Orthologs.
Gene Information
Type Protein coding
Genomic Location Chromosome 19:18683677-18782333
Strand Forward strand
Band p13.11
Transcripts
ENST00000338797 ENSP00000345001
ENST00000321949 ENSP00000323332
ENST00000601916 ENSP00000469285
ENST00000594658 ENSP00000468893
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 8 experimentally validated interaction(s) in this database.
They are also associated with 1 interaction(s) predicted by orthology.
Experimentally validated
Total 8 [view]
Protein-Protein 8 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 1 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0005515 protein binding
GO:0008140 cAMP response element binding protein binding
Biological Process
GO:0006351 transcription, DNA-templated
GO:0007613 memory
GO:0016032 viral process
GO:0032793 positive regulation of CREB transcription factor activity
GO:0045944 positive regulation of transcription from RNA polymerase II promoter
GO:0051289 protein homotetramerization
GO:0060081 membrane hyperpolarization
Cellular Component
GO:0005634 nucleus
GO:0005737 cytoplasm
GO:0005886 plasma membrane
Orthologs
Species
Mus musculus
Bos taurus
Gene ID
Gene Order
ENSMUSG00000003575
View Gene Order
ENSBTAG00000010379
Not yet available
Pathways
NETPATH
REACTOME
KEGG
INOH
PID NCI
ap1_pathway
AP-1 transcription factor network
Cross-References
SwissProt Q6UUV9
TrEMBL
UniProt Splice Variant
Entrez Gene 23373
UniGene Hs.371096 Hs.713464
RefSeq NM_015321 NM_001098482
HUGO HGNC:16062
OMIM 607536
CCDS CCDS32963 CCDS42525
HPRD 06339
IMGT
EMBL AB014516 AC003107 AC004476 AC006123 AK024089 AY040323 AY040324 AY186997 AY186998 AY360171 BC017075 BC023614 BC028050 CH471106
GenPept AAC97072 AAH17075 AAH23614 AAH28050 AAK93832 AAK93833 AAP12462 AAP12463 AAQ98856 BAA31591 BAB14822 EAW84730
RNA Seq Atlas 23373

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca