Version 5.4
Homo sapiens Gene: PYCRL
Summary
InnateDB Gene IDBG-38808.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol PYCRL
Gene Name pyrroline-5-carboxylate reductase-like
Synonyms
Species Homo sapiens
Ensembl Gene ENSG00000104524
Encoded Proteins
IDBP-38810
pyrroline-5-carboxylate reductase-like
IDBP-38812
pyrroline-5-carboxylate reductase-like
IDBP-377518
pyrroline-5-carboxylate reductase-like
IDBP-377524
pyrroline-5-carboxylate reductase-like
IDBP-807959
pyrroline-5-carboxylate reductase-like
IDBP-807970
pyrroline-5-carboxylate reductase-like
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary Currently no Entrez Summary Available. You might want to check the Summary Sections of the Orthologs.
Gene Information
Type Protein coding
Genomic Location Chromosome 8:143603913-143609773
Strand Reverse strand
Band q24.3
Transcripts
ENST00000220966 ENSP00000220966
ENST00000377579 ENSP00000366802
ENST00000433751 ENSP00000404493
ENST00000447926 ENSP00000401804
ENST00000495276 ENSP00000480945
ENST00000462036 ENSP00000478138
ENST00000482616
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 19 experimentally validated interaction(s) in this database.
Experimentally validated
Total 19 [view]
Protein-Protein 19 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Gene Ontology

Molecular Function
Accession GO Term
GO:0004735 pyrroline-5-carboxylate reductase activity
GO:0005515 protein binding
GO:0042802 identical protein binding
Biological Process
GO:0006561 proline biosynthetic process
GO:0055114 oxidation-reduction process
GO:0055129 L-proline biosynthetic process
Cellular Component
Orthologs
Species
Mus musculus
Bos taurus
Gene ID
Gene Order
ENSMUSG00000022571
View Gene Order
ENSBTAG00000016810
Not yet available
Pathways
NETPATH
REACTOME
KEGG
hsa00330
Arginine and proline metabolism pathway
INOH
INOH website
Arginine Proline metabolism pathway
PID NCI
Cross-References
SwissProt
TrEMBL
UniProt Splice Variant
Entrez Gene
UniGene Hs.165186
RefSeq NM_023078
HUGO
OMIM
CCDS CCDS6407
HPRD 15196
IMGT
EMBL
GenPept
RNA Seq Atlas

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca