Version 5.4
Homo sapiens Gene: ADAP2
Summary
InnateDB Gene IDBG-39331.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol ADAP2
Gene Name ArfGAP with dual PH domains 2
Synonyms
Species Homo sapiens
Ensembl Gene ENSG00000184060
Encoded Proteins
IDBP-39333
ArfGAP with dual PH domains 2
IDBP-758527
IDBP-759470
IDBP-757832
IDBP-761495
IDBP-764321
IDBP-759278
IDBP-760146
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary Currently no Entrez Summary Available. You might want to check the Summary Sections of the Orthologs.
Gene Information
Type Protein coding
Genomic Location Chromosome 17:30906344-30959322
Strand Forward strand
Band q11.2
Transcripts
ENST00000330889 ENSP00000329468
ENST00000480980
ENST00000470962
ENST00000581548 ENSP00000467079
ENST00000580526 ENSP00000462832
ENST00000583688
ENST00000585130 ENSP00000464120
ENST00000580525 ENSP00000464121
ENST00000581285 ENSP00000464155
ENST00000584989 ENSP00000462634
ENST00000584828 ENSP00000463649
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 10 experimentally validated interaction(s) in this database.
Experimentally validated
Total 10 [view]
Protein-Protein 10 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Gene Ontology

Molecular Function
Accession GO Term
GO:0005515 protein binding
GO:0005546 phosphatidylinositol-4,5-bisphosphate binding
GO:0005547 phosphatidylinositol-3,4,5-trisphosphate binding
GO:0008060 ARF GTPase activator activity
GO:0008270 zinc ion binding
GO:0030674 protein binding, bridging
GO:0043325 phosphatidylinositol-3,4-bisphosphate binding
GO:0043533 inositol 1,3,4,5 tetrakisphosphate binding
Biological Process
GO:0007507 heart development
GO:0032312 regulation of ARF GTPase activity
GO:0043547 positive regulation of GTPase activity
Cellular Component
GO:0005737 cytoplasm
GO:0005740 mitochondrial envelope
GO:0005886 plasma membrane
Orthologs
Species
Mus musculus
Bos taurus
Gene ID
Gene Order
ENSMUSG00000020709
View Gene Order
ENSBTAG00000003334
Not yet available
Cross-References
SwissProt
TrEMBL
UniProt Splice Variant
Entrez Gene
UniGene Hs.514063 Hs.623367 Hs.628547
RefSeq NM_018404 XM_005258008
HUGO
OMIM
CCDS CCDS11261
HPRD 16357
IMGT
EMBL
GenPept
RNA Seq Atlas

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca