Version 5.4
Homo sapiens Gene: TSSK6
Summary
InnateDB Gene IDBG-39903.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol TSSK6
Gene Name testis-specific serine kinase 6
Synonyms
Species Homo sapiens
Ensembl Gene ENSG00000178093
Encoded Proteins
IDBP-762811
IDBP-766175
IDBP-809949
testis-specific serine kinase 6
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This intronless gene encodes a member of the CAMK (calcium/calmodulin-dependent) serine/threonine protein kinase family. The encoded kinase has a broad expression pattern but is described as testis-specific due to effects on fertility. Male mice which lack the gene encoding a highly similar protein are sterile and have morphologically abnormal sperm. [provided by RefSeq, Jan 2012]
Gene Information
Type Protein coding
Genomic Location Chromosome 19:19512418-19515685
Strand Reverse strand
Band p13.11
Transcripts
ENST00000585580 ENSP00000466477
ENST00000587522 ENSP00000466056
ENST00000602623 ENSP00000473413
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 12 experimentally validated interaction(s) in this database.
Experimentally validated
Total 12 [view]
Protein-Protein 11 [view]
Protein-DNA 1 [view]
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Gene Ontology

Molecular Function
Accession GO Term
GO:0000287 magnesium ion binding
GO:0004672 protein kinase activity
GO:0004674 protein serine/threonine kinase activity
GO:0004713 protein tyrosine kinase activity
GO:0005515 protein binding
GO:0005524 ATP binding
GO:0016772 transferase activity, transferring phosphorus-containing groups
GO:0016773 phosphotransferase activity, alcohol group as acceptor
Biological Process
GO:0006468 protein phosphorylation
GO:0007275 multicellular organismal development
GO:0009103 lipopolysaccharide biosynthetic process
GO:0035092 sperm chromatin condensation
Cellular Component
GO:0005634 nucleus
GO:0016020 membrane
Orthologs
Species
Mus musculus
Bos taurus
Gene ID
Gene Order
ENSMUSG00000047654
View Gene Order
ENSBTAG00000006649
Not yet available
Cross-References
SwissProt Q9BXA6
TrEMBL A0A024R7Q5 R4GMZ2
UniProt Splice Variant
Entrez Gene 83983
UniGene Hs.532711 Hs.666780
RefSeq NM_032037
HUGO HGNC:30410
OMIM 610712
CCDS CCDS12403
HPRD 15441
IMGT
EMBL AC011448 AF329483 AF348077 AK058166 AK172841 AK313767 BC014611 CH471106
GenPept AAH14611 AAK29414 AAK48827 BAB71697 BAD18805 BAG36505 EAW84824 EAW84825
RNA Seq Atlas 83983

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca