Version 5.4
Homo sapiens Gene: P2RY8
Summary
InnateDB Gene IDBG-40192.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol P2RY8
Gene Name purinergic receptor P2Y, G-protein coupled, 8
Synonyms
Species Homo sapiens
Ensembl Gene ENSG00000182162
Encoded Proteins
IDBP-40194
purinergic receptor P2Y, G-protein coupled, 8
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary The protein encoded by this gene belongs to the family of G-protein coupled receptors, that are preferentially activated by adenosine and uridine nucleotides. This gene is moderately expressed in undifferentiated HL60 cells, and is located on both chromosomes X and Y. [provided by RefSeq, Jul 2008]
Gene Information
Type Protein coding
Genomic Location Chromosome X:1462572-1537107
Strand Reverse strand
Band p22.33
Transcripts
ENST00000381297 ENSP00000370697
ENST00000460672
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 1 experimentally validated interaction(s) in this database.
Experimentally validated
Total 1 [view]
Protein-Protein 1 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Gene Ontology

Molecular Function
Accession GO Term
GO:0004930 G-protein coupled receptor activity
GO:0045028 G-protein coupled purinergic nucleotide receptor activity
Biological Process
GO:0007186 G-protein coupled receptor signaling pathway
GO:0035589 G-protein coupled purinergic nucleotide receptor signaling pathway
Cellular Component
GO:0005886 plasma membrane
GO:0016021 integral component of membrane
Orthologs
No orthologs found for this gene
Pathways
NETPATH
REACTOME
KEGG
hsa04080
Neuroactive ligand-receptor interaction pathway
INOH
PID NCI
Cross-References
SwissProt Q86VZ1
TrEMBL
UniProt Splice Variant
Entrez Gene 286530
UniGene Hs.111377 Hs.605264
RefSeq NM_178129 XM_005274429 XM_005274430 XM_005274778 XM_005274779 XM_006724443 XM_006724864
HUGO HGNC:15524
OMIM 300525
CCDS CCDS14115
HPRD
IMGT
EMBL AL683870 BC043610
GenPept AAH43610 CAI39849
RNA Seq Atlas 286530

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca