|
InnateDB Gene
|
IDBG-403485.3
|
|
Last Modified
|
2014-10-13 [Report errors or provide feedback]
|
|
Gene Symbol
|
KRT8P3
|
|
Gene Name
|
keratin 8 pseudogene 3
|
|
Synonyms
|
CARD2; CK-8; CK8; CYK8; K2C8; K8; KO
|
|
Species
|
Homo sapiens
|
|
Ensembl Gene
|
ENSG00000254285
|
|
Encoded Proteins
|
|
|
Protein Structure
|
|
|
Useful resources
|
Stemformatics
EHFPI
ImmGen
|
| Summary |
This gene is a member of the type II keratin family clustered on the long arm of chromosome 12. Type I and type II keratins heteropolymerize to form intermediate-sized filaments in the cytoplasm of epithelial cells. The product of this gene typically dimerizes with keratin 18 to form an intermediate filament in simple single-layered epithelial cells. This protein plays a role in maintaining cellular structural integrity and also functions in signal transduction and cellular differentiation. Mutations in this gene cause cryptogenic cirrhosis. Alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, Jan 2012]
|
| Type |
processed_pseudogene
|
|
Genomic Location
|
Chromosome 8:61578220-61579668
|
|
Strand
|
Forward strand
|
|
Band
|
q12.3
|
|
Transcripts
|
|
|
Number of Interactions
|
This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
|
|
|
No orthologs found for this gene |
|
SwissProt
|
|
|
TrEMBL
|
|
|
UniProt Splice Variant
|
|
|
Entrez Gene
|
|
|
UniGene
|
|
|
RefSeq
|
|
|
HUGO
|
|
|
OMIM
|
|
|
CCDS
|
|
| HPRD |
|
|
IMGT
|
|
|
EMBL
|
|
|
GenPept
|
|
|
RNA Seq Atlas
|
|
|
|
|
Version 5.4