Homo sapiens Gene: ADH1C
Summary
InnateDB Gene IDBG-408498.2
Last Modified 2012-02-14 [Report errors or provide feedback]
Gene Symbol ADH1C
Gene Name alcohol dehydrogenase 1C (class I), gamma polypeptide
Synonyms ADH3;
Species Homo sapiens
Ensembl Gene ENSG00000248144
Encoded Proteins
alcohol dehydrogenase 1C (class I), gamma polypeptide
Protein Structure
Entrez Gene
Summary This gene encodes class I alcohol dehydrogenase, gamma subunit, which is a member of the alcohol dehydrogenase family. Members of this enzyme family metabolize a wide variety of substrates, including ethanol, retinol, other aliphatic alcohols, hydroxysteroids, and lipid peroxidation products. Class I alcohol dehydrogenase, consisting of several homo- and heterodimers of alpha, beta, and gamma subunits, exhibits high activity for ethanol oxidation and plays a major role in ethanol catabolism. Three genes encoding alpha, beta and gamma subunits are tandemly organized in a genomic segment as a gene cluster. [provided by RefSeq, Jul 2008]
Gene Information
Type polymorphic_pseudogene
Genomic Location Chromosome 4:100257649-100274184
Strand Reverse strand
Band q23
Transcripts
ENST00000511397
ENST00000505942
ENST00000510055
ENST00000515683 ENSP00000426083
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
Orthologs
No orthologs found for this gene
Pathways
NETPATH
REACTOME
KEGG
Glycolysis / Gluconeogenesis pathway
Retinol metabolism pathway
Fatty acid metabolism pathway
Tyrosine metabolism pathway
Metabolism of xenobiotics by cytochrome P450 pathway
Drug metabolism - cytochrome P450 pathway
Metabolic pathways pathway
INOH
PID BIOCARTA
PID NCI
Cross-References
SwissProt
TrEMBL
UniProt Splice Variant
Entrez Gene 126
UniGene Hs.654537
RefSeq NM_000669
HUGO 251
OMIM 103730
CCDS
HPRD 00066
IMGT
EMBL
GenPept
ImmGen ADH1C (murine)
RNA Seq Atlas 126