Version 5.4
| Homo sapiens Gene: PCDHGC4 | |||||||||
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| Summary | |||||||||
| InnateDB Gene | IDBG-408923.3 | ||||||||
| Last Modified | 2014-10-13 [Report errors or provide feedback] | ||||||||
| Gene Symbol | PCDHGC4 | ||||||||
| Gene Name | protocadherin gamma subfamily C, 4 | ||||||||
| Synonyms | |||||||||
| Species | Homo sapiens | ||||||||
| Ensembl Gene | ENSG00000242419 | ||||||||
| Encoded Proteins |
protocadherin gamma subfamily C, 4
protocadherin gamma subfamily C, 4
protocadherin gamma subfamily C, 4
protocadherin gamma subfamily C, 4
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| Protein Structure | |||||||||
| Useful resources | Stemformatics EHFPI ImmGen | ||||||||
| Entrez Gene | |||||||||
| Summary |
This gene is a member of the protocadherin gamma gene cluster, one of three related clusters tandemly linked on chromosome five. These gene clusters have an immunoglobulin-like organization, suggesting that a novel mechanism may be involved in their regulation and expression. The gamma gene cluster includes 22 genes divided into 3 subfamilies. Subfamily A contains 12 genes, subfamily B contains 7 genes and 2 pseudogenes, and the more distantly related subfamily C contains 3 genes. The tandem array of 22 large, variable region exons are followed by a constant region, containing 3 exons shared by all genes in the cluster. Each variable region exon encodes the extracellular region, which includes 6 cadherin ectodomains and a transmembrane region. The constant region exons encode the common cytoplasmic region. These neural cadherin-like cell adhesion proteins most likely play a critical role in the establishment and function of specific cell-cell connections in the brain. Alternative splicing has been described for the gamma cluster genes. [provided by RefSeq, Jul 2008] |
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| Gene Information | |||||||||
| Type | Protein coding | ||||||||
| Genomic Location | Chromosome 5:141484997-141512979 | ||||||||
| Strand | Forward strand | ||||||||
| Band | q31.3 | ||||||||
| Transcripts |
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| Interactions | |||||||||
| Number of Interactions |
This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
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| Gene Ontology | |||||||||
Molecular Function |
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| Biological Process |
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| Cellular Component |
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| Orthologs | |||||||||
| No orthologs found for this gene | |||||||||
| Cross-References | |||||||||
| SwissProt | |||||||||
| TrEMBL | A4FU17 | ||||||||
| UniProt Splice Variant | |||||||||
| Entrez Gene | 56098 | ||||||||
| UniGene | |||||||||
| RefSeq | NM_032406 NM_018928 | ||||||||
| HUGO | HGNC:8717 | ||||||||
| OMIM | 606305 | ||||||||
| CCDS | CCDS75349 CCDS4262 | ||||||||
| HPRD | |||||||||
| IMGT | |||||||||
| EMBL | BC101036 | ||||||||
| GenPept | AAI01037 | ||||||||
| RNA Seq Atlas | 56098 | ||||||||