Homo sapiens Gene: GYPB | |||||||
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Summary | |||||||
InnateDB Gene | IDBG-408950.3 | ||||||
Last Modified | 2014-10-13 [Report errors or provide feedback] | ||||||
Gene Symbol | GYPB | ||||||
Gene Name | glycophorin B (MNS blood group) | ||||||
Synonyms | CD235b; GPB; GPB.NY; GpMiIII; GYPHe.NY; HGpMiIII; HGpMiVI; HGpMiX; MNS; PAS-3; SS | ||||||
Species | Homo sapiens | ||||||
Ensembl Gene | ENSG00000250361 | ||||||
Encoded Proteins |
glycophorin B (MNS blood group)
glycophorin B (MNS blood group)
glycophorin B (MNS blood group)
glycophorin B (MNS blood group)
glycophorin B (MNS blood group)
glycophorin B (MNS blood group)
glycophorin B (MNS blood group)
glycophorin B (MNS blood group)
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Protein Structure | |||||||
Useful resources | Stemformatics EHFPI ImmGen | ||||||
Entrez Gene | |||||||
Summary |
Glycophorins A (GYPA) and B (GYPB) are major sialoglycoproteins of the human erythrocyte membrane which bear the antigenic determinants for the MN and Ss blood groups. GYPB gene consists of 5 exons and has 97% sequence homology with GYPA from the 5' UTR to the coding sequence encoding the first 45 amino acids. In addition to the M or N and S or s antigens, that commonly occur in all populations, about 40 related variant phenotypes have been identified. These variants include all the variants of the Miltenberger complex and several isoforms of Sta; also, Dantu, Sat, He, Mg, and deletion variants Ena, S-s-U- and Mk. Most of the variants are the result of gene recombinations between GYPA and GYPB. [provided by RefSeq, Jul 2008] Glycophorins A (GYPA) and B (GYPB) are major sialoglycoproteins of the human erythrocyte membrane which bear the antigenic determinants for the MN and Ss blood groups. GYPB gene consists of 5 exons and has 97%% sequence homology with GYPA from the 5\' UTR to the coding sequence encoding the first 45 amino acids. In addition to the M or N and S or s antigens, that commonly occur in all populations, about 40 related variant phenotypes have been identified. These variants include all the variants of the Miltenberger complex and several isoforms of Sta; also, Dantu, Sat, He, Mg, and deletion variants Ena, S-s-U- and Mk. Most of the variants are the result of gene recombinations between GYPA and GYPB. [provided by RefSeq, Jul 2008] |
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Gene Information | |||||||
Type | Protein coding | ||||||
Genomic Location | Chromosome 4:143996104-144019345 | ||||||
Strand | Reverse strand | ||||||
Band | q31.21 | ||||||
Transcripts | |||||||
Interactions | |||||||
Number of Interactions |
This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
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Gene Ontology | |||||||
Molecular Function |
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Biological Process |
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Cellular Component |
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Orthologs | |||||||
No orthologs found for this gene | |||||||
Pathways | |||||||
NETPATH | |||||||
REACTOME | |||||||
KEGG |
Malaria pathway
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INOH | |||||||
PID NCI | |||||||
Cross-References | |||||||
SwissProt | |||||||
TrEMBL | |||||||
UniProt Splice Variant | |||||||
Entrez Gene | |||||||
UniGene | |||||||
RefSeq | NM_002100 XM_005262969 | ||||||
HUGO | |||||||
OMIM | |||||||
CCDS | CCDS54809 | ||||||
HPRD | 00201 | ||||||
IMGT | |||||||
EMBL | |||||||
GenPept | |||||||
RNA Seq Atlas | |||||||