Version 5.4
| Homo sapiens Gene: RNF103-CHMP3 | |||||
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| Summary | |||||
| InnateDB Gene | IDBG-408956.4 | ||||
| Last Modified | 2014-10-13 [Report errors or provide feedback] | ||||
| Gene Symbol | RNF103-CHMP3 | ||||
| Gene Name | RNF103-CHMP3 readthrough | ||||
| Synonyms | |||||
| Species | Homo sapiens | ||||
| Ensembl Gene | ENSG00000249884 | ||||
| Encoded Proteins |
RNF103-VPS24 readthrough
RNF103-CHMP3 readthrough
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| Protein Structure | |||||
| Useful resources | Stemformatics EHFPI ImmGen | ||||
| Entrez Gene | |||||
| Summary |
The protein encoded by this gene contains a RING-H2 finger, a motif known to be involved in protein-protein and protein-DNA interactions. This gene is highly expressed in normal cerebellum, but not in the cerebral cortex. The expression of the rat counterpart in the frontal cortex and hippocampus was shown to be induced by elctroconvulsive treatment (ECT) as well as chronic antidepressant treatment, suggesting that this gene may be a molecular target for ECT and antidepressants. The protein is a ubiquitin ligase that functions in the endoplasmic reticulum-associated degradation pathway. Alternative splicing of this gene results in multiple transcript variants. Read-through transcription also exists between this gene and the downstream CHMP3 (charged multivesicular body protein 3) gene. [provided by RefSeq, Oct 2011] |
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| Gene Information | |||||
| Type | Protein coding | ||||
| Genomic Location | Chromosome 2:86505668-86721122 | ||||
| Strand | Reverse strand | ||||
| Band | p11.2 | ||||
| Transcripts |
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| Interactions | |||||
| Number of Interactions |
This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
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| Gene Ontology | |||||
Molecular Function |
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| Biological Process |
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| Cellular Component |
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| Orthologs | |||||
| No orthologs found for this gene | |||||
| Pathways | |||||
| NETPATH | |||||
| REACTOME | |||||
| KEGG |
Endocytosis pathway
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| INOH | |||||
| PID NCI | |||||
| Cross-References | |||||
| SwissProt | |||||
| TrEMBL | |||||
| UniProt Splice Variant | |||||
| Entrez Gene | |||||
| UniGene | |||||
| RefSeq | NM_001198954 | ||||
| HUGO | |||||
| OMIM | |||||
| CCDS | CCDS56128 | ||||
| HPRD | |||||
| IMGT | |||||
| EMBL | |||||
| GenPept | |||||
| RNA Seq Atlas | |||||