Homo sapiens Gene: ASB14
Summary
InnateDB Gene IDBG-409168.3
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol ASB14
Gene Name ankyrin repeat and SOCS box containing 14
Synonyms
Species Homo sapiens
Ensembl Gene ENSG00000239388
Encoded Proteins
ankyrin repeat and SOCS box containing 14
ankyrin repeat and SOCS box containing 14
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary The protein encoded by this gene is a member of the ankyrin repeat and SOCS box-containing (ASB) family of proteins. They contain ankyrin repeat sequence and a SOCS box domain. The SOCS box serves to couple suppressor of cytokine signalling (SOCS) proteins and their binding partners with the elongin B and C complex, possibly targeting them for degradation. Alternative splicing results in multiple transcript variants encoding different isoforms.[provided by RefSeq, Dec 2008]
Gene Information
Type Protein coding
Genomic Location Chromosome 3:57268347-57292682
Strand Reverse strand
Band p14.3
Transcripts
ENST00000389601 ENSP00000374252
ENST00000487349 ENSP00000419199
ENST00000515033
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 21 experimentally validated interaction(s) in this database.
Experimentally validated
Total 21 [view]
Protein-Protein 21 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Gene Ontology

Molecular Function
Accession GO Term
GO:0005515 protein binding
Biological Process
GO:0016567 protein ubiquitination
GO:0035556 intracellular signal transduction
Cellular Component
Orthologs
Species
Mus musculus
Bos taurus
Gene ID
Gene Order
Not yet available
Pathways
NETPATH
REACTOME
Antigen processing: Ubiquitination & Proteasome degradation pathway
Adaptive Immune System pathway
Immune System pathway
Class I MHC mediated antigen processing & presentation pathway
KEGG
INOH
PID NCI
Cross-References
SwissProt
TrEMBL
UniProt Splice Variant
Entrez Gene
UniGene Hs.740755
RefSeq NM_001142733 NM_130387 XM_006712982
HUGO
OMIM
CCDS CCDS46856
HPRD 10668
IMGT
EMBL
GenPept
RNA Seq Atlas