Homo sapiens Gene: AMY2B
Summary
InnateDB Gene IDBG-409447.3
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol AMY2B
Gene Name amylase, alpha 2B (pancreatic)
Synonyms AMY2; AMY3; HXA
Species Homo sapiens
Ensembl Gene ENSG00000240038
Encoded Proteins
amylase, alpha 2B (pancreatic)
amylase, alpha 2B (pancreatic)
amylase, alpha 2B (pancreatic)
amylase, alpha 2B (pancreatic)
amylase, alpha 2B (pancreatic)
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary Amylases are secreted proteins that hydrolyze 1,4-alpha-glucoside bonds in oligosaccharides and polysaccharides, and thus catalyze the first step in digestion of dietary starch and glycogen. The human genome has a cluster of several amylase genes that are expressed at high levels in either salivary gland or pancreas. This gene encodes an amylase isoenzyme produced by the pancreas. [provided by RefSeq, Jul 2008]
Amylases are secreted proteins that hydrolyze 1,4-alpha-glucoside bonds in oligosaccharides and polysaccharides, and thus catalyze the first step in digestion of dietary starch and glycogen. The human genome has a cluster of several amylase genes that are expressed at high levels in either salivary gland or pancreas. This gene encodes an amylase isoenzyme produced by the pancreas. [provided by RefSeq, Jun 2013]
Gene Information
Type Protein coding
Genomic Location Chromosome 1:103553815-103579534
Strand Forward strand
Band p21.1
Transcripts
ENST00000361355 ENSP00000354610
ENST00000435302 ENSP00000391423
ENST00000453959 ENSP00000401627
ENST00000477657 ENSP00000433347
ENST00000491397
ENST00000462971
ENST00000481821
ENST00000610648 ENSP00000481588
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 1 experimentally validated interaction(s) in this database.
Experimentally validated
Total 1 [view]
Protein-Protein 1 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Gene Ontology

Molecular Function
Accession GO Term
GO:0003824 catalytic activity
GO:0004556 alpha-amylase activity
GO:0043169 cation binding
GO:0046872 metal ion binding
Biological Process
GO:0005975 carbohydrate metabolic process
GO:0007586 digestion
Cellular Component
GO:0005576 extracellular region
Orthologs
No orthologs found for this gene
Pathways
NETPATH
REACTOME
Digestion of dietary carbohydrate pathway
Myoclonic epilepsy of Lafora pathway
Metabolism of carbohydrates pathway
Metabolism pathway
Disease pathway
Glycogen storage diseases pathway
KEGG
Starch and sucrose metabolism pathway
Pancreatic secretion pathway
Carbohydrate digestion and absorption pathway
INOH
PID NCI
Cross-References
SwissProt P19961
TrEMBL B3KTI1 C9J2Z5 C9JWK7
UniProt Splice Variant
Entrez Gene 648740
UniGene Hs.721681
RefSeq NM_020978
HUGO HGNC:478
OMIM 104660
CCDS CCDS782
HPRD
IMGT
EMBL AC105272 AK095605 AK127047 BC011179 BC020861 CH471097 D90097 M18670 M24895 X07057
GenPept AAA35525 AAA51725 AAH11179 AAH20861 BAA14130 BAG53093 BAG54429 CAA30100 EAW72902 EAW72903 EAW72904
RNA Seq Atlas 280 648740