Version 5.4
Homo sapiens Gene: RBMS2
Summary
InnateDB Gene IDBG-41243.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol RBMS2
Gene Name RNA binding motif, single stranded interacting protein 2
Synonyms SCR3
Species Homo sapiens
Ensembl Gene ENSG00000076067
Encoded Proteins
IDBP-41245
RNA binding motif, single stranded interacting protein 2
IDBP-589378
RNA binding motif, single stranded interacting protein 2
IDBP-599183
RNA binding motif, single stranded interacting protein 2
IDBP-596218
RNA binding motif, single stranded interacting protein 2
IDBP-596815
RNA binding motif, single stranded interacting protein 2
IDBP-602952
RNA binding motif, single stranded interacting protein 2
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary The protein encoded by this gene is a member of a small family of proteins which bind single stranded DNA/RNA. These proteins are characterized by the presence of two sets of ribonucleoprotein consensus sequence (RNP-CS) that contain conserved motifs, RNP1 and RNP2, originally described in RNA binding proteins, and required for DNA binding. The RBMS proteins have been implicated in such diverse functions as DNA replication, gene transcription, cell cycle progression and apoptosis. This protein was isolated by phenotypic complementation of cdc2 and cdc13 mutants of yeast and is thought to suppress cdc2 and cdc13 mutants through the induction of translation of cdc2. [provided by RefSeq, Jul 2008]
Gene Information
Type Protein coding
Genomic Location Chromosome 12:56521929-56596196
Strand Forward strand
Band q13.3
Transcripts
ENST00000262031 ENSP00000262031
ENST00000552247 ENSP00000447426
ENST00000551369 ENSP00000447699
ENST00000552916 ENSP00000450127
ENST00000549945
ENST00000550726 ENSP00000449678
ENST00000542360 ENSP00000443486
ENST00000552228
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 12 experimentally validated interaction(s) in this database.
Experimentally validated
Total 12 [view]
Protein-Protein 12 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Gene Ontology

Molecular Function
Accession GO Term
GO:0000166 nucleotide binding
GO:0003676 nucleic acid binding
GO:0003723 RNA binding
GO:0044822 poly(A) RNA binding
Biological Process
GO:0006396 RNA processing
Cellular Component
GO:0005634 nucleus
Orthologs
Species
Mus musculus
Bos taurus
Gene ID
Gene Order
ENSMUSG00000040043
View Gene Order
ENSBTAG00000017830
Not yet available
Cross-References
SwissProt
TrEMBL
UniProt Splice Variant
Entrez Gene
UniGene Hs.505729
RefSeq NM_002898 XM_005269059 XM_005269061 XM_006719544
HUGO
OMIM
CCDS CCDS8923
HPRD 03860
IMGT
EMBL
GenPept
RNA Seq Atlas

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca