InnateDB: Systems Biology of the Innate Immune Response

Homo sapiens Gene: ARSF

Summary

InnateDB Gene

IDBG-41332.5

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

ARSF

Gene Name

arylsulfatase F

Synonyms

ASF

Species

Homo sapiens

Ensembl Gene

ENSG00000062096

Encoded Proteins

IDBP-41334

arylsulfatase F

IDBP-41336

arylsulfatase F

Protein Structure

Useful resources

Stemformatics EHFPI ImmGen

Entrez Gene

Summary

This gene is a member of the sulfatase family, and more specifically, the arylsulfatase subfamily. Members of the subfamily share similarity in sequence and splice sites, and are clustered together on chromosome X, suggesting that they are derived from recent gene duplication events. Sulfatases are essential for the correct composition of bone and cartilage matrix. The activity of this protein, unlike that of arylsulfatase E, is not inhibited by warfarin. Multiple alternatively spliced variants, encoding the same protein, have been identified.[provided by RefSeq, Jan 2011]

Gene Information

Type

Protein coding

Genomic Location

Chromosome X:3041471-3112726

Strand

Forward strand

Band

p22.33

Transcripts

ENST00000381127	ENSP00000370519
ENST00000359361	ENSP00000352319

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 1 experimentally validated interaction(s) in this database.

Experimentally validated
Total	1 [view]
Protein-Protein	1 [view]
Protein-DNA	0
Protein-RNA	0
DNA-DNA	0
RNA-RNA	0
DNA-RNA	0

Gene Ontology

Molecular Function

Accession	GO Term
GO:0003824	catalytic activity
GO:0004065	arylsulfatase activity
GO:0008484	sulfuric ester hydrolase activity
GO:0046872	metal ion binding

Biological Process

GO:0006665	sphingolipid metabolic process
GO:0006687	glycosphingolipid metabolic process
GO:0008152	metabolic process
GO:0043687	post-translational protein modification
GO:0044267	cellular protein metabolic process
GO:0044281	small molecule metabolic process