Version 5.4
Homo sapiens Gene: UQCRFS1
Summary
InnateDB Gene IDBG-41696.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol UQCRFS1
Gene Name ubiquinol-cytochrome c reductase, Rieske iron-sulfur polypeptide 1
Synonyms RIP1; RIS1; RISP; UQCR5
Species Homo sapiens
Ensembl Gene ENSG00000169021
Encoded Proteins
IDBP-41698
ubiquinol-cytochrome c reductase, Rieske iron-sulfur polypeptide 1
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary Currently no Entrez Summary Available. You might want to check the Summary Sections of the Orthologs.
Gene Information
Type Protein coding
Genomic Location Chromosome 19:29205321-29213541
Strand Reverse strand
Band q12
Transcripts
ENST00000304863 ENSP00000306397
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 33 experimentally validated interaction(s) in this database.
Experimentally validated
Total 33 [view]
Protein-Protein 33 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Gene Ontology

Molecular Function
Accession GO Term
GO:0005515 protein binding
GO:0008121 ubiquinol-cytochrome-c reductase activity
GO:0016491 oxidoreductase activity
GO:0032403 protein complex binding
GO:0046872 metal ion binding
GO:0051537 2 iron, 2 sulfur cluster binding
Biological Process
GO:0009725 response to hormone
GO:0022904 respiratory electron transport chain
GO:0042493 response to drug
GO:0044237 cellular metabolic process
GO:0044281 small molecule metabolic process
GO:0046677 response to antibiotic
GO:0055114 oxidation-reduction process
GO:1902600 hydrogen ion transmembrane transport
Cellular Component
GO:0005739 mitochondrion
GO:0005743 mitochondrial inner membrane
GO:0005750 mitochondrial respiratory chain complex III
GO:0031966 mitochondrial membrane
Orthologs
Species
Mus musculus
Bos taurus
Gene ID
Gene Order
ENSMUSG00000038462
View Gene Order
ENSBTAG00000046786
Not yet available
Pathways
NETPATH
REACTOME
REACT_22393
Respiratory electron transport pathway
REACT_6305
Respiratory electron transport, ATP synthesis by chemiosmotic coupling, and heat production by uncoupling proteins. pathway
REACT_111083
The citric acid (TCA) cycle and respiratory electron transport pathway
REACT_111217
Metabolism pathway
KEGG
hsa05010
Alzheimer's disease pathway
hsa00190
Oxidative phosphorylation pathway
hsa05012
Parkinson's disease pathway
hsa05016
Huntington's disease pathway
hsa04260
Cardiac muscle contraction pathway
INOH
PID NCI
Cross-References
SwissProt P47985
TrEMBL
UniProt Splice Variant
Entrez Gene 7386
UniGene
RefSeq NM_006003
HUGO HGNC:12587
OMIM 191327
CCDS CCDS12415
HPRD
IMGT
EMBL AC007786 AK291134 BC000649 BC010035 BC067832 L32917 L32977
GenPept AAC41754 AAD38242 AAH00649 AAH10035 AAH67832 BAF83823
RNA Seq Atlas 7386

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca