Homo sapiens Gene: CDH20
Summary
InnateDB Gene IDBG-4206.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol CDH20
Gene Name cadherin 20, type 2
Synonyms
Species Homo sapiens
Ensembl Gene ENSG00000101542
Encoded Proteins
cadherin 20, type 2
cadherin 20, type 2
cadherin 20, type 2
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene is a type II classical cadherin from the cadherin superfamily and one of three cadherin 7-like genes located in a cluster on chromosome 18. The encoded membrane protein is a calcium dependent cell-cell adhesion glycoprotein comprised of five extracellular cadherin repeats, a transmembrane region and a highly conserved cytoplasmic tail. Type II (atypical) cadherins are defined based on their lack of a HAV cell adhesion recognition sequence specific to type I cadherins. Since disturbance of intracellular adhesion is a prerequisite for invasion and metastasis of tumor cells, cadherins are considered prime candidates for tumor suppressor genes. [provided by RefSeq, Jul 2008]
Gene Information
Type Protein coding
Genomic Location Chromosome 18:61333582-61555773
Strand Forward strand
Band q21.33
Transcripts
ENST00000262717 ENSP00000262717
ENST00000536675 ENSP00000444767
ENST00000538374 ENSP00000442226
ENST00000587582
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
Gene Ontology

Molecular Function
Accession GO Term
GO:0005509 calcium ion binding
Biological Process
GO:0007156 homophilic cell adhesion
Cellular Component
GO:0005886 plasma membrane
GO:0016020 membrane
GO:0016021 integral component of membrane
Orthologs
Species
Mus musculus
Bos taurus
Gene ID
Gene Order
Not yet available
Cross-References
SwissProt
TrEMBL
UniProt Splice Variant
Entrez Gene
UniGene Hs.671510
RefSeq NM_031891 XM_005266682 XM_005266684
HUGO
OMIM
CCDS CCDS11977
HPRD 10429
IMGT
EMBL
GenPept
RNA Seq Atlas