Version 5.4
Homo sapiens Gene: VCX
Summary
InnateDB Gene IDBG-42091.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol VCX
Gene Name variable charge, X-linked
Synonyms
Species Homo sapiens
Ensembl Gene ENSG00000182583
Encoded Proteins
IDBP-42093
variable charge, X-linked
IDBP-42095
variable charge, X-linked
IDBP-808074
variable charge, X-linked
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene belongs to the VCX/Y gene family, which has multiple members on both X and Y chromosomes, and all are expressed exclusively in male germ cells. The X-linked members are clustered on chromosome Xp22 and Y-linked members are two identical copies of the gene within a palindromic region on Yq11. The family members share a high degree of sequence identity, with the exception that a 30-bp unit is tandemly repeated in X-linked members but occurs only once in Y-linked members. The VCX gene cluster is polymorphic in terms of copy number; different individuals may have a different number of VCX genes. VCX/Y genes encode small and highly charged proteins of unknown function. The presence of a putative bipartite nuclear localization signal suggests that VCX/Y members are nuclear proteins. This gene contains 10 repeats of the 30-bp unit. [provided by RefSeq, Jul 2008]
Gene Information
Type Protein coding
Genomic Location Chromosome X:7842262-7844143
Strand Forward strand
Band p22.31
Transcripts
ENST00000381059 ENSP00000370447
ENST00000341408 ENSP00000344144
ENST00000620630 ENSP00000484419
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
Gene Ontology

Molecular Function
Accession GO Term
GO:0003682 chromatin binding
Biological Process
GO:0006325 chromatin organization
GO:0007283 spermatogenesis
GO:0042255 ribosome assembly
Cellular Component
GO:0005634 nucleus
GO:0005730 nucleolus
Orthologs
No orthologs found for this gene
Cross-References
SwissProt
TrEMBL
UniProt Splice Variant
Entrez Gene 26609
UniGene
RefSeq NM_013452
HUGO HGNC:12667
OMIM 300229
CCDS CCDS14128
HPRD
IMGT
EMBL
GenPept
RNA Seq Atlas 26609

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca