Version 5.4
Homo sapiens Gene: PDCD5
Summary
InnateDB Gene IDBG-42196.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol PDCD5
Gene Name programmed cell death 5
Synonyms TFAR19
Species Homo sapiens
Ensembl Gene ENSG00000105185
Encoded Proteins
IDBP-42198
programmed cell death 5
IDBP-42200
programmed cell death 5
IDBP-813504
programmed cell death 5
IDBP-765655
IDBP-764010
IDBP-762995
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene encodes a protein that is upregulated during apoptosis where it translocates rapidly from the cytoplasm to the nucleus. The encoded protein may be an important regulator of K(lysine) acetyltransferase 5 (a protein involved in transcription, DNA damage response and cell cycle control) by inhibiting its proteasome-dependent degradation. Pseudogenes have been identified on chromosomes 5 and 12 [provided by RefSeq, Dec 2010]
Gene Information
Type Protein coding
Genomic Location Chromosome 19:32581068-32587452
Strand Forward strand
Band q13.11
Transcripts
ENST00000221784 ENSP00000221784
ENST00000379316 ENSP00000368620
ENST00000419343 ENSP00000476525
ENST00000592786 ENSP00000468741
ENST00000586316
ENST00000586035 ENSP00000467737
ENST00000590247 ENSP00000466214
ENST00000588622
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 31 experimentally validated interaction(s) in this database.
Experimentally validated
Total 31 [view]
Protein-Protein 31 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Gene Ontology

Molecular Function
Accession GO Term
GO:0003677 DNA binding
Biological Process
GO:0006915 apoptotic process
GO:0043065 positive regulation of apoptotic process
Cellular Component
GO:0005634 nucleus
GO:0005737 cytoplasm
GO:0070062 extracellular vesicular exosome
Orthologs
Species
Mus musculus
Bos taurus
Gene ID
Gene Order
ENSMUSG00000030417
View Gene Order
ENSBTAG00000009304
Not yet available
Cross-References
SwissProt
TrEMBL
UniProt Splice Variant
Entrez Gene
UniGene Hs.599519 Hs.609345 Hs.613550 Hs.684085
RefSeq NM_004708 XM_005259392
HUGO
OMIM
CCDS CCDS12423
HPRD 06843
IMGT
EMBL
GenPept
RNA Seq Atlas

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca